The term `spatial hemineglect' refers collectively to disorders of spatial cognition, which concern specific sectors of space with reference to a given coordinate system. Patients with cerebral lesions involving the posterior-inferior parietal and the premotor cortex, most often in the right hemisphere, sometimes fail to explore the extra-personal and personal sectors of space contralateral to ...

The purpose of this study was to determine if patients with hemispheric brain lesions and subsequent paresis demonstrated a correlation between the perception of joint position sense and the ability to combine component parts of the limb synergies. Twenty-one adult patients with 6-week to 87-month histories of unilateral, hemispheric, paralytic brain lesions were evaluated by each of two tests....

Background: A demyelinating lesion can present as a space occupying in Magnetic Resonance Imaging (MRI) brain. Lesions that have diameter greater than 2 cm is referred tumefactive lesion. These lesions mimic brain tumor, namely glioma or primary central nervous system lymphoma. Case presentation: We two female patients over 30 years old who presented with limb weakness. Their MRI demonstrated t...

Somatotopic distribution of motor cortex and sensory fibers is theoretically fully understood. We present a case of stroke, mimicking peripheral palsy, with finger paralysis attributed to cortical lesion. The patient’s brain MRI may be useful to further understand the somatotopic representation of fingers in precentral and postcentral gyrus.

Understanding the intensity characteristics of brain lesions is key for defining image-based biomarkers in neurological studies and predicting disease burden outcome. In this work, we present a novel foreground-based generative method modelling local lesion that can both generate synthetic on healthy images synthesize subject-specific pseudo-healthy from pathological images. Furthermore, propos...

background: alzheimer’s disease was known as a progressive neurodegenerative disorder in the elderly and is characterized by dementia and severe neuronal loss in the some regions of brain such as nucleus basalis magnocellularis. it plays an important role in the brain functions such as learning and memory. loss of cholinergic neurons of nucleus basalis magnocellularis by ibotenic acid can commo...

Postnatal neuronal migration modulates circuit formation and function throughout life is conserved among species. Pathological conditions activate the generation of neuroblasts in ventricular-subventricular zone (V-SVZ) promote their towards a lesion. However, generally terminate before reaching lesion site unless intrinsic capacity modified or environment improved. It important to understand w...

BACKGROUND AND PURPOSE In MS, the total brain lesion volume and spatial distribution of lesions across the brain vary widely among individual patients. We hypothesized that spatial distribution may be partially driven by genetic predisposition, and we aimed to explore relations among candidate genes and the spatial distribution of white matter brain lesions in MS. MATERIAL AND METHODS Genotyp...