نتایج جستجو برای: brain toxicity
تعداد نتایج: 585041 فیلتر نتایج به سال:
Many fishes are ammonotelic but some species can detoxify ammonia to glutamine or urea. Certain fish species can accumulate high levels of ammonia in the brain or defense against ammonia toxicity by enhancing the effectiveness of ammonia excretion through active NH4+transport, manipulation of ambient pH, or reduction in ammonia permeability through the branchial and cutaneous epithelia. Recent ...
Introduction: From 1986 to 2005, for 20 years about 2010 renal transplantations(TX) have been performed in our center mainly from unrelated kidney donor. Various bacterial, viral, fungal infections and malignancy after transplantation have been reported due to use of suppressive medications. After 20 years of experience with kidney transplantation in Iran, there are many reports of various ...
the need of aquarists for proper and safe disinfection of fish with chloramine-t (cl-t) necessitates toxico/pathologic examinations. this study assays toxicity level of cl-t and histopathologic changes of gills, liver, kidney and brain of treated zebrafish (danio rerio). groups of 10 zebrafish were treated with 0 (control), 5, 10, 15, 30, 50,100 and 200 mg/l of cl– t. mortality was recorded a...
The effect of Cotinine, active metabolite of nicotine, on Aβ1-42 neurotoxicity was investigated. Cotinine possesses a longer plasma half-life, lower toxicity and it is a partial agonist of the nicotinic acetylcholine receptors (nAChR). Cotinine prolonged the survival of cortical neurons exposed to Aβ1-42. These results indicated that cotinine has a neuroprotective effect by inhibition of the fo...
The major challenge to treat Parkinson’s disease (PD) is penetration of target molecule into the brain to improve the efficacy of drugs. To achieve better brain penetration and targeted delivery, 1,9-Pyrazoloanthrone (1,9-P) loaded liposomes were developed by solvent injection technique using ultrasonication and evaluated for particle size, morphology, entrapment efficiency, FT-IR, and in-vitro...
The major challenge to treat Parkinson’s disease (PD) is penetration of target molecule into the brain to improve the efficacy of drugs. To achieve better brain penetration and targeted delivery, 1,9-Pyrazoloanthrone (1,9-P) loaded liposomes were developed by solvent injection technique using ultrasonication and evaluated for particle size, morphology, entrapment efficiency, FT-IR, and in-vitro...
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