In a systematic effort to identify a potent antiproliferative agent, four complexes of vanadium containing maltol and deferiprone ligands were synthesized and evaluated for their cytotoxic activity against five human and animal cancer cell lines, including human breast cancer cells (MCF-7), human cervix epithelial carcinoma (HeLa), human colon cancer cell line (HT-29), human leukemia cell line ...

cancer is a group of diseases characterized by uncontrolled proliferation of abnormal cells. because of the severe side effects and resistance to the traditional chemotherapeutic agents, the necessity for discovery of new anticancer drugs is a crucial topic. in the present study we synthesized new derivatives of 2-(4-fluorophenyl)- n -halophenylacetamide and assessed their cytotoxicity against ...

Background: Berberine and Nano-curcumin are two herbal medicines with strong anti-cancer effects on tumor cells, but low toxicity on normal cells, when used alone. Breast cancer is known as the most common cancer in women and second deadly one. In this study, we evaluated the cytotoxicity effects of combination Berberine and Nano-curcumin in breast cancer cell line to see whether they have furt...

In continuation of previous research, the anticancer screening formulation herbal syrup Vinca extract was performed. The performed as per reported literature method. cancer on two Human cell lines. These lines were Lung Cancer line A549 and Breast Cell MCF7. found to be devoid properties.

elevated expression of the drug efflux transporter abcg2 seems to correlate with multidrug resistance of cancer cells. specific cox-2 inhibitor celecoxib has been shown to enhance the sensitivity of cancer cells to anticancer drugs. to clarify whether abcg2 inhibition is involved in the sensitizing effect of celecoxib, we investigated whether the expression of abcg2 in breast cancer cell lines ...

the two stable isotopes of hydrogen, protium (1h) and deuterium (2h) differ in their physicochemical nature. deuterium-depleted water (ddw) significantly inhibited the growth rate of different tumor cell lines in culture media and xenotransplanted mda-mb-231, mcf-7 human breast adenocarcinomas and pc-3 human prostate tumors in vivo. the apoptosis-triggering effect of ddw was demonstrated both i...

In vitro studies on cancer cell lines still constitutes a major part of cancer research. It is very important that the researchers consider the importance of basic conditions of working with different cell lines. To the best of authors knowledge, this study is the first one to report the effect of seeding density on the growth curve of three human cancer cell lines. These cell lines include hum...

conclusions these results show that zen and α-zol enhance the rate of cell division in er positive cells and therefore, exposure to this mycotoxin may increase the risk of breast cancer. results the results obtained from the present study demonstrated that both zen and α-zol enhance the cell viability of mcf-7 especially at low doses (1 - 500 ng/ml) and at a high dose of 125µg/ml after 24 and 4...

 ABSTRACT Background: The aims of this study were to assay the activity of adenosine deaminase (ADA) in estrogen receptor positive (MCF-7) and negative (MDA-MB468) breast cancer cell lines. Methods: MDA-MB468 and MCF-7 breast cancer cell lines were cultured in complete medium, striped serum with and without 0.0 1~-LM diethylstilbestrol (DES), complete medium in the presence and absence of 111M ...