results based on the recent researches, certain mmps play critical role in breast cancer initiation, invasion, and metastasis. they can be regarded as predictive biomarkers of primary diagnosis and prognosis of breast cancer and have predictive value for evaluation of disease, tumor recurrence, invading of tumor cells to other sites and therapeutic outcomes. conclusions in summary, the results ...

Background: Breast cancer is the most commonly diagnosed and the leading cause of cancer death among females worldwide. The rate of breast cancer incidence among Iranian women is 17% of all cancers, it has been ranked first in Iran. This study aimed to investigate the factors affecting axillary lymph node involvement in female patients with breast cancer. Methods: A cross-sectional study was c...

Myofibroblastoma of the breast (MFB) is a rare benign mesenchymal tumor breast. A case giant myofibroblastic tumor, which rarely reported in literature, was recently diagnosed our department. We also analyzed clinicopathological features MFB to improve understanding and avoid misdiagnosis.

the value of clinical use of tumor markers cea and ca15-3 for early detection of recurrent breast cancer still is a controversial. this study was investigated relationship between tumor markers cea and ca15-3 and recurrence breast cancer. data regarding 147 women who had breast cancer were entered into the study. patients were reviewed for 120 months after treatment. maximum time for relapse wa...

background and purpose: breast cancer is the most common cause of cancer-specific mortality among women worldwide. this study aimed at investigating the epidemiological, clinical, and pathological characteristics of breast cancer among patients attending baghban clinic in sari. materials and methods: the patients’ records (2008-2014) were used and data including age, gender, marital status, men...

background: trace elements play an important role in a number of biological processes. astaxanthin (asx), a carotoid pigment found in certain marine plant and animals, has shown anti cancer and anti free radical properties. this work intended to understand the effect of astaxanthin in breast cancer (invasive ductal carcinoma, idc) by using micro-pixe method. for this aim the concentration of tr...

Background: Alteration in peripheral blood lymphocytes (PBLs) is usually investigated to provide an evidence of the host immune responses to tumor antigens. The tumor infiltrating NK cells interact most closely with the tumor cells and more accurately reflect tumor host interactions. Objective: To analyze peripheral blood and tumor associated Natural Killer (NK) cells in patients with breast ca...

Background: Despite recent advances in diagnosis and treatment, breast cancer remains a leading cause of death in women worldwide. Long non-coding RNAs are a new class of RNA molecules that have been shown to participate in tumorigenesis. The aim of this study was to investigate the expression of lncUSMycN in tumor samples and to evaluate its potential role in the breast cancer cell line. Metho...