It has been claimed that barbiturates uncouple oxidative phosphorylations (Brody & Bain, 1954; Brody, 1955). These authors have demonstrated that during the oxidation of pyruvate by liver and brain mitochondria, phosphate uptake was lowered proportionately more than oxygen uptake. Support for the uncoupling theory was derived from certain similarities between the barbiturates and 2:4dinitrophen...

The statistical properties (fluctuations) of heartbeat intervals (RR intervals) in ECG are studied and compared with the predictions of Random Matrix Theory (RMT). It is found that heartbeat intervals only locally exhibit the fluctuation patterns (universality) predicted by the RMT. This finding shows that heartbeat dynamics is of the mixed type where regular and irregular (chaotic) regimes coe...

Leslie C. Thompson,* Nathan A. Holland,* Ryan J. Snyder, Bin Luo, Daniel P. Becak, Jillian T. Odom, Benjamin S. Harrison, Jared M. Brown, Kymberly M. Gowdy, and Christopher J. Wingard Department of Physiology, Brody School of Medicine at East Carolina University, Greenville, North Carolina; Department of Pharmacology & Toxicology, Brody School of Medicine at East Carolina University, Greenville...

Hornstein (1998) argued, like Brody (1995), that a theory with both chain and move is redundant, that one of them should be eliminated. He presented two arguments that the concept of A-chains should not be part of the grammar. In my comments (Brody 1999), I showed that the arguments for this way of eliminating the redundancy are flawed and that their background is dubious. Hornstein in his repl...

by potassium. Circ Res 12: 415-421, 1963 7. Surawicz B, Mazzoleni A: Role of potassium in ventricular asystole. In Sudden Cardiac Death, edited by B Surawicz, ED Pellegrino. New York, Grune & Stratton, 1964, pp 90-96 8. Gettes LS, Surawicz B: Effects of low and high concentrations of potassium on the simultaneously recorded Purkinje and ventricular action potentials of the perfused pig moderato...

by potassium. Circ Res 12: 415-421, 1963 7. Surawicz B, Mazzoleni A: Role of potassium in ventricular asystole. In Sudden Cardiac Death, edited by B Surawicz, ED Pellegrino. New York, Grune & Stratton, 1964, pp 90-96 8. Gettes LS, Surawicz B: Effects of low and high concentrations of potassium on the simultaneously recorded Purkinje and ventricular action potentials of the perfused pig moderato...