Abstract: Snoring is an important sign of sleep-related breathing disorders (SRBD), of the upper airway resistance syndrome (UARS), and of the obstructive sleep apnea (OSA). Snoring is a symptom of nasal obstruction and is associated with cardiovascular diseases. Roommates or bed partners are also suffered by snorers. In-house monitoring of snoring is very useful for evaluation by bed partner o...

The aim of the present study was the development and subsequent validation of a simple, precise and stability-indicating reversed phase HPLC method for the simultaneous determination of guaifenesin, terbutaline sulphate and bromhexine hydrochloride in the presence of their potential impurities in a single run. The photolytic as well as hydrolytic impurities were detected as 3,5-dihydroxybenzoic...