Asthma is a chronic disease characterized by increased bronchial responsiveness ranging in degree from mild ~o severe. AU:Way inflammation has been receiving 1ncrcased auenuon as the major mechanism in bronchial hypcrrcsponsiveness. Many stimuli known to induce airwa~ inflam~ation ~lso i.ncrease bronchial reactivity, e.g. v~ral rcsp1ratory mfectJOns, ozone, antigens and chem1ca ls such as tolue...

Twenty seven aspirin sensitive asthmatic patients were studied to determine the relationship between non-specific bronchial responsiveness to inhaled histamine and the degree of sensitivity to aspirin (aspirin threshold dose). No correlation was found between provocative concentration of histamine (PC20H) and aspirin threshold dose. In 11 patients the influence of aspirin desensitisation on bro...

The prevalence of asthma and bronchial hyperresponsiveness (BHR) tends to decrease in male children but increase in female children in the transition from childhood to adolescence. Hormonal factors may be involved in the natural history of asthma during this period. In a prospective study of Montreal school children, the authors examined the determinants of BHR according to the child's pubertal...

ZAPATA-ORTIZ, VICENTE, RAMIRO CASTRO DE LA MATA, ENRIQUE FERNANDEZ, ARTURO GEU, AND LUIS BATALLA. Bronchial circulation in high altitudes. Am. J. Physiol. 2 I 2 (6) : I #j41468. 1967. -Bronchial circulation and bronchopulmonary anastomoses have been studied in two groups of sheep native to the high Andes (above 4,000 m) and to the Peruvian coastal plain. The high altitude-adapted animals showed...

The bronchial hyperreactivity characteristic of asthma may be related to enhanced parasympathetic nervous activity. We postulated that an abnormality in the autonomic control of airway caliber might be reflected by a parallel change in the reflex control of heart rate. We examined the heart-rate variations induced by deep breathing (respiratory sinus arrhythmia), the Valsalva maneuver, and stan...

I n recent years there has been special focus on the increased occurrence of asthma and bronchial responsiveness among top athletes within endurance sports. As early as 1989, an increase in nonspecific bronchial responsiveness after heavy endurance training was found in young competitive swimmers [1]. Later, reports were made concerning increased prevalence of asthma and bronchial hyperresponsi...