Given the importance of cross-disciplinary research (CDR), facilitating CDR effectiveness is a priority for many institutions and funding agencies. There are a number of CDR types, however, and the effectiveness of facilitation efforts will require sensitivity to that diversity. This article presents a method characterizing a spectrum of CDR designed to inform facilitation efforts that relies o...

As a country which frequently suffers from natural disasters, especially earthquakes, China has implemented its own disaster management system to respond to them. The Chinese government gained practical experiences on how to respond to severe earthquakes after the 2008 Wenchuan Earthquake and 2010 Yushu Earthquake. Although China has done a lot to improve its response operations, challenges rem...

Background: Phospho-modulation of SNARE function has not yet known. Results: Phospho-SNAP-25 was de-phosphorylated by protein phosphatase-1 whose activity was regulated by PRIP, thus regulating exocytosis. Conclusion: Protein phosphatase-1 whose activity is regulated by PRIP, is the major phosphatase responsible for the de-phosphorylation of SNAP-25. Significance: The results provide the first ...

Bioactivation of vitamin D consists of two sequential hydroxylation steps to produce 1α,25-dihydroxyvitamin D3. It is clear that the second or 1α-hydroxylation step is carried out by a single enzyme, 25-hydroxyvitamin D 1α-hydroxylase CYP27B1. However, it is not certain what enzyme or enzymes are responsible for the initial 25-hydroxylation. An excellent case has been made for vitamin D 25-hydr...

25-Dihydrosaframycin A(AR1) and 21-decyano-25-dihydrosaframycin A(AR3) were produced by the microbial conversion of saframycin A(SA). Efficient conversion of SA to AR, and AR3 was observed with Rhodococcus amidophifus IFM 144. Though the antimicrobial activity of AR, was one tenth that of SA, the in vitro antitumor activity of AR1 was found to be equivalent to that of SA. In contrast, AR, was b...

One important determinant of the speed and success of transition will be the efficiency of transformation and development of the infrastructure sectors. A great deal of attention has been paid to issues such as privatisation, restructuring, user prices, and terms of access in these sectors, regarding both developed and developing countries. Some issues regarding vertical restructuring are notab...

Research in virtual teams and distributed work argues that the lack of collocation places an overhead on the performance potential of large, globally distributed teams. In this paper, we revisit this tenet through a case study of Free/Libre Open Source Software (FLOSS) development to demonstrate how globally dispersed FLOSS communities manage to overcome the problem of geographic separation of ...

The International Successful School Principalship Project (ISSPP) has been actively conducting research about the work of successful principals since 2001. Findings from four project books and eight models derived from this project are synthesised into a model of successful school leadership. Building on Gurr, Drysdale and Mulford’s earlier model, the work of school leaders is described as enga...