Background: Preliminary clinical trials showed that ginger improved lipid profile in type 2 diabetes patients (T2D). This trial was carried out to determine the effect of ginger on blood lipid and lipoproteins in T2D. Methods: this is a randomized, double-blind, placebo-controlled trial on 88 T2D conducted in. The patients were randomly divided into two groups of ginger (GG) and placebo (PG), t...

It has been previously shown that transfection activity of cationic liposome/DNA lipoplexes delivered systemically is drastically inhibited by lipoproteins (Tandia, B. M., Vandenbranden, M., Wattiez, R., Lakhdar, Z., Ruysschaert, J. M., and Elouahabi, A. (2003) Mol Ther. 8, 264-273). In this work, we have compared the binding/uptake and transfection activities of DOTAP (N-[1-(2,3-dioleoyloxy)pr...

BACKGROUND Lipids and lipoproteins are recognized as the most important modifiable risk factors for cardiovascular disease. Although reference values for the major lipoproteins, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol, and triglycerides, have been collected in numerous studies and cohorts, complete contemporary percentile-based reference values are unde...

Infectious and many non-infectious diseases share common molecular mechanisms. Among them, oxidative stress the subsequent inflammatory reaction are of particular note. Metabolic disorders induced by external agents, be they bacterial or viral pathogens, excessive calorie intake, poor-quality nutrients, environmental factors produce an imbalance between production free radicals endogenous antio...

objective(s) the aim of this study was to investigate the effects of aerobics, pilates exercises and low calorie diet on leptin levels and some lipid profiles and anthropometric factors in sedentary women. materials and methods forty six women (age 36.41±3.47) were recruited and divided into four groups: aerobic exercise group (ex), pilates exercise group (pilates), low calorie diet (lcd) and c...

Objective: The risk of cardiovascular disease increased in diabetic patients due to lipoprotein metabolism disorder and insulin resistance. There is different type of dyslipidemia in diabetic patient. The nicotinic acid (niacin) is categorized as vitamin B family and decreases low-density lipoproteins (LDL) and triglyceride (TG) level and increases high-density lipoproteins (HDL). The aim of th...

Plasma lipoproteins from patients with familial lecithin:cholesterol acyltransferase (LCAT) deficiency have been fractioned by preparative ultra-centrifugation and gel filtration and their lipid content and reactivity studied. All of the lipoproteins are abnormal with respect to lipid concentration or relative lipid content. The low density lipoproteins (LDL) and high density lipoproteins (HDL)...

introduction atherosclerosis is a disease which begins during childhood. oxidation of lipoproteins is an important factor implicated in atherosclerosis. vitamin c decreases blood serum lipids and may inhibit atherosclerosis. this study was designed to observe the effect of ascorbic acid on blood serum lipids in male rabbits fed high-cholesterol diet. methods twenty white male rabbits were weigh...

The disease abetalipoproteinemia results in intriguing disturbances of lipid transport (2, 3). Included among its manifestations are an inability to form chylomicrons (4) and the lowest concentrations of plasma lipids detected in any human disorder. In this familial syndrome it is possible that the elaboration of beta lipoprotein, or more strictly its beta or B apoprotein, is primarily affected...