نتایج جستجو برای: c2n h2d
تعداد نتایج: 314 فیلتر نتایج به سال:
Changes in the fibroblast growth factor receptor (FGFR) axis are often associated with prostate cancer (CaP) progression. We have used chemically induced dimerization (CID) to elucidate the individual contributions of FGFR1 and FGFR2 to tumor etiology. Novel CaP cell lines stably expressing CID/AP20187-inducible FGFR1 (iFGFR1) and iFGFR2 were made using the tumorigenic transgenic adenocarcinoma...
We report here the results of the analytical validation of assays that measure HER2 total protein (H2T) and HER2 homodimer (H2D) expression in Formalin Fixed Paraffin Embedded (FFPE) breast cancer tumors as well as cell line controls. The assays are based on the VeraTag technology platform and are commercially available through a central CAP-accredited clinical reference laboratory. The accurac...
Relative equilibria of molecules are classical trajectories corresponding to steady rotations about stationary axes during which the shape of the molecule does not change. They can be used to explain and predict features of quantum spectra at high values of the total angular momentum J in much the same way that absolute equilibria are used at low J. This paper gives a classi® cation of the symm...
For graphs G1, G2, G3, the three-color Ramsey number R(G1, G2, G3) is the smallest integer n such that if we arbitrarily color the edges of the complete graph of order n with 3 colors, then it contains a monochromatic copy of Gi in color i, for some 1 ≤ i ≤ 3. First, we prove that the conjectured equality R(C2n, C2n, C2n) = 4n, if true, implies that R(P2n+1, P2n+1, P2n+1) = 4n + 1 for all n ≥ 3...
Immunodominance hierarchies are a substantial, but poorly understood, characteristic of CD8(+) T cell-mediated immunity. Factors influencing the differential responses to the influenza A virus nucleoprotein (NP(366-374)) and acid polymerase (PA(224-233)) peptides presented by H2D(b) have been analyzed by disabling (N5--> Q substitution) these peptides in their native configuration, then express...
For graphs G1, G2, G3, the three-color Ramsey number R(G1, G2, G3) is the smallest integer n such that if we arbitrarily color the edges of the complete graph of order n with 3 colors, then it contains a monochromatic copy of Gi in color i, for some 1 ≤ i ≤ 3. First, we prove that the conjectured equality R(C2n, C2n, C2n) = 4n, if true, implies that R(P2n+1, P2n+1, P2n+1) = 4n + 1 for all n ≥ 3...
Chemical oxidation is useful for solubilizing and separating endohedral metallofullerenes, as demonstrated here by a separation of three categories of Gd@C2n species and by the solubilization of Tm@C60+ and Tm@C70+ for the first time.
Changes in the fibroblast growth factor receptor (FGFR) axis are often associated with prostate cancer (CaP) progression. We have used chemically induced dimerization (CID) to elucidate the individual contributions of FGFR1 and FGFR2 to tumor etiology. Novel CaP cell lines stably expressing CID/AP20187-inducible FGFR1 (iFGFR1) and iFGFR2 were made using the tumorigenic transgenic adenocarcinoma...
While the abundance of elemental deuterium is relatively low (D/H ~ a few 1E-5), orders magnitude higher D/H ratios have been found for many interstellar molecules, enhanced by fractionation. In cold molecular clouds (T < 20K) fractionation driven H2D+ ion, whereas at temperatures > 20-30K) gas-phase deuteration controlled reactions with CH2D+ and C2HD+. role in driving chemistry well understoo...
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