The aim of this study is to determine the effects of 1,25(OH)2D3 and its analogues on tumor growth and body weight, changes in plasma ionized calcium, parathyroid hormone-related protein (PTHrP) production, bone resorption, and the distribution of the 1,25(OH)2D3 receptor (VDR) on tumors in nude mice-bearing the canine adenocarcinoma (CAC-8). Thirty-seven nude mice were implanted subcutaneously...

BACKGROUND The prognostic value of coronary artery calcium (CAC) scoring on top of myocardial perfusion imaging with single-photon emission computed tomography (SPECT) in patients suspected for coronary artery disease is not well established. METHODS AND RESULTS Four thousand eight hundred ninety-seven symptomatic patients without a history of coronary artery disease referred for SPECT and CA...

OBJECTIVES This study aimed to investigate the independent and joint associations between family history of myocardial infarction (FH) and coronary artery calcification (CAC) with incident coronary heart disease (CHD). BACKGROUND FH and CAC are associated with each other and with incident CHD. It is not known whether FH retains its predictive value after CAC results are accounted for. METHO...

OBJECTIVES The aim of this study was to evaluate the impact of coronary artery calcium (CAC) burden and regional distribution on the need for and type of future coronary revascularization-percutaneous versus surgical (coronary artery bypass graft [CABG])-among asymptomatic subjects. BACKGROUND The need for coronary revascularization and the chosen mode of revascularization are thought to be f...

OBJECTIVE To compare the incidence and extent of coronary artery calcification (CAC) as measured by electron beam computed tomography (EBCT) in patients with systemic lupus erythematosus (SLE) and controls, and to identify variables associated with CAC in patients with SLE. METHODS Female patients with SLE and matched controls were recruited; EBCT of the coronary arteries was performed, and l...

Connection Admission Control (CAC) is a preventive congestion control mechanism and it is essential for providing Quality of Service (QoS) requirements for calls established over ATM. The strategies for CAC in an ATM network can be classij?ed into two categories: measurement-based CAC and traffic descriptor-based CAC. Both categories have their advantages and disadvantages. This paper proposes ...

Our previous genetic analysis of synaptic mechanisms in Drosophila identified a temperature-sensitive paralytic mutant of the voltage-gated calcium channel alpha1 subunit gene, cacophony (cac). Electrophysiological studies in this mutant, designated cac(TS2), indicated cac encodes a primary calcium channel alpha1 subunit functioning in neurotransmitter release. To further examine the functions ...

OBJECTIVES Coronary artery calcium (CAC) is a strong and independent predictor of cardiovascular disease (CVD) risk. This study assesses reproducibility of automatic CAC scoring on radiotherapy planning computed tomography (CT) scans of breast cancer patients, and examines its association with traditional cardiovascular risk factors. METHODS This study included 561 breast cancer patients unde...

BACKGROUND Coronary artery calcification (CAC) is an extensive and common complication in patients with end-stage renal disease (ESRD). The aim of this study was to assess prospectively the change in CAC over a 2-year period and to identify the factors that may be associated with CAC progression in ESRD patients. METHODS The final analysis was performed on 40 of 43 stable haemodialysis patien...

Introduction: Coronary artery calcification (CAC) is known as sub-clinical atherosclerosis and its detection is a marker for coronary artery disease (CAD). The conventional cardiovascular risk factors used to quantify the estimated 10-year coronary event risk comprise dyslipidaemia, hypertension, diabetes mellitus, obesity, smoking and family history of CAD. Their relationship with significant ...