application of therapeutic gene transfer in the treatment of genetic diseases is a notable progress but there are some disadvantages and limitations in it. the process of overcoming these barriers is a drastic change in gene delivery. recently, calcium phosphate nanoparticles alone, or in combination with viral and nonviral vectors, were found to have a positive effect on gene transfer especial...

Hyperphosphatemia has an important role in the development of secondary hyperparathyroidism and bone disease in patients with end-stage renal disease (ESRD). The most effective method of phosphate elimination lies with phosphate binders, the agent that more commonly used, calcium carbonate, is not an ideal binding agent. In this regard, calcium acetate has been reported to have more or at least...

although salivary alkaline phosphatase (alp) can balance de- and remineralization processes of enamel, there is no evidence regarding its effects on the concentrations of calcium and phosphate in saliva. the present study aims to determine the relationship between salivary alp activity and the concentrations of calcium and phosphate in saliva. in this cross-sectional study, we evaluated salivar...

PURPOSE This study aimed to explore if initiation of biomimetic apatite nucleation can be used to enhance osteoblast response to biodegradable tissue regeneration composite membranes. MATERIALS AND METHODS Bioactive thermoplastic composites consisting of poly(ε-caprolactone/DL-lactide) and bioactive glass (BAG) were prepared at different stages of biomimetic calcium phosphate deposition by im...

This article presents the results of a study of the efficiency of silanation process of calcium phosphate glasses particles and its effect on the bioactivity behavior of glass- poly(methyl methacrylate) (PMMA) composites. Two different calcium phosphate glasses: 44.5CaO-44.5P2 O5 -11Na2 O (BV11) and 44.5CaO-44.5P2 O5 -6Na2 O-5TiO2 (G5) were synthesized and treated with silane coupling agent. Th...

background: despite widespread clinical uses of resin-modifi ed glass-ionomers (rmgis), their sealing ability is still a concern. this study evaluated the effect of delayed light activation (dla) of rmgi on marginal sealing in differently pretreated cavities. materials and methods: in this in vitro study, two standardized class v cavities were prepared on the buccal and lingual surfaces of 56 s...