The paper presents the results regarding the electron beam irradiation of fresh Salvia Officinalis and Calendula Officinalis. Irradiation is already a well-known decontamination method, but it received less attention for medicinal plants, especially on fresh herbs. Microbial load behaviour, antioxidant activity, and enzymatic inhibition activity were measured for doses up to 50 kGy. Herbs are d...

UNLABELLED PHARMACOLOGICAL RELEVANCE: Presentation of the scratch assay as a convenient and inexpensive in vitro tool to gain first insights in the wound healing potential of plant extracts and natural compounds. AIM OF THE STUDY The present study deals with the optimization of the scratch assay which can be used as an in vitro model for quantification of fibroblast migration to and prolifera...

Bacterial vaginosis (BV) is a common disorder among women of reproductive age. This study aimed to compare the effect of a Calendula officinalis extract-based cream and metronidazole on BV among women of reproductive age. In this study, 80 women of reproductive age with BV were randomly assigned to the C. officinalis (n = 40) or metronidazole (n = 40). Diagnosis of BV was confirmed when at leas...

BACKGROUND In patients with ulcerative colitis (UC), the repeated cycle of injury and repair of intestinal mucosa has been reported to increase the risk of colon cancer. So, a safe and efficient therapy is required for the treatment and prophylaxis for the disease.This study aims to investigate the efficacy of Calendula officinalis extract in treatment of experimentally induced ulcerative colit...

Calendula officinalis Linn (Asteraceae), is an aromatic annual herb, which is used in Traditional System of Medicine to treat various diseases like anti-inflammatory, antitumour, antispasmodic. The reported constituents are flavonoids, glycosides and saponins. From literature it was found that the quantification work was not carried out. It is considered to contain Quercetin, confirmed by TLC a...

Reactive oxygen species (ROS) generated from UV-B radiation have the capacity to cause oxidative decomposition which leads to the formation of toxic components as well as lipid peroxidation. Considering this fact, the present study was performed to evaluate the effect of a cream (O/W) containing the essential oil of Calendula officinalis on biochemical parameters of the skin of albino rats agai...

INTRODUCTION Diaper dermatitis (DD) is a common inflammatory disorder among children and infants. The objective of the present randomized and double-blind trial was to compare the therapeutic efficacies of aloe vera cream and Calendula officinalis ointment on the frequency and severity of DD in children. METHODS Sixty-six infants with DD (aged < 3 years) were randomized to receive either aloe...

BACKGROUND The use of medicinal plants is an option for livestock farmers who are not allowed to use allopathic drugs under certified organic programs or cannot afford to use allopathic drugs for minor health problems of livestock. METHODS In 2003 we conducted semi-structured interviews with 60 participants obtained using a purposive sample. Medicinal plants are used to treat a range of condi...