objective: inflammation is one of the major components of asthma. our aim was to evaluate the effects of c. sativus extract on total and differential white blood cells (wbc) count in lung lavage fluid (llf) of ovalbumin-sensitized rats. materials and methods: forty rats were divided into five groups (n = 8 for each group) as control (c), sensitized with injection and inhalation of ovalbumin (oa...

The effect of administration of calf thymus extract (CTE) with protein concentration of 1.8mg/ml was studied using two groups of day old layer chicks. Both the groups were vaccinated with 'F' and 'R2B' strains of New Castle Disease Virus (NDV) vaccines on 7th day and 8th week respectively. One group was administered with 1.8mg of thymic proteins intraperitoneally, one week prior and one week af...

The thermodynamic parameters of interaction between calf thymus histone H A and dodecyl trimethyl ammonium bromide (DTAB), a cationic surfactant, in aqueous solutions of pH 3.2, 6.4 and 10.0 were measured over a wide range of DTAB concentrations by equilibrium dialysis at 27°C and 37°C and are discussed. The data are used to determine the free energy from the Wyman binding potential theore...

Existing methodology for surface tension measurements based on drop shapes suffers from the shortcoming that it is not capable to function at very low surface tension if the liquid dispersion is opaque, such as therapeutic lung surfactants at clinically relevant concentrations. The novel configuration proposed here removes the two big restrictions, i.e., the film leakage problem that is encount...

many studies have been performed for treatment or prevention of pulmonary fibrosis. however, no effective treatment has been found yet. the aim of this study was to investigate the effect of grape seed extract on bleomycin-induced lung fibrosis in rat. hydroalcoholic extract of grape seed (vitis vinifera) was prepared using maceration method. nmri rats weighing 250-300 g were given single intra...

Beta(2)-adrenergic agonists cause a release of pulmonary surfactant into lung airways. The surfactant phospholipids maintain the patency of the conducting airways, but this function is inhibited by plasma proteins entering an inflamed airway. The physical behavior of the surfactant can be studied with a pulsating bubble surfactometer and a capillary surfactometer. Calf lung surfactant extract w...

INTRODUCTION Available literature suggests that the advantage of animal-derived surfactants over first-generation synthetic agents derives from the presence of surface-active proteins and their phospholipid content. Here we summarize the results of clinical trials comparing animal-derived surfactant preparations with other animal-derived surfactants and with both first-and second-generation syn...

BACKGROUND Diarrhea because of Salmonella infection is a cause of neonatal calf diarrhea. The stimulation of passive immunity in the calf by vaccinating the dam for Salmonella has shown some success in previous studies; however, there are no data on the use of currently licensed vaccines in the United States. OBJECTIVE To determine whether vaccinating cows at dry-off with a commercially avail...