Disinhibition of reflexes is a problem amongst spastic patients, for it limits a smooth and efficient execution of motor functions during gait. Treadmill belt accelerations may potentially be used to measure reflexes during walking, i.e. by dorsal flexing the ankle and stretching the calf muscles, while decelerations show the modulation of reflexes during a reduction of sensory feedback. The ai...

Studies on BC3H-1 myocytes suggest that the insulin-induced increase in cellular diacylglycerol level mediates the insulin-stimulated glucose transport in these cells (Standaert, M. L., Farese, R. V., Cooper, D. R., and Pollet, R. J. (1988) J. Biol. Chem. 263, 8696-8705). The present study tested whether diacylglycerol could mediate the insulin-induced and exercise-induced increases in glucose ...

Studies on BC3H-1 myocytes suggest that the insulin-induced increase in cellular diacylglycerol level mediates the insulin-stimulated glucose transport in these cells (Standaert, M. L., Farese, R. V., Cooper, D. R., and Pollet, R. J. (1988) J. Biol. Chem. 263,86968705). The present study tested whether diacylglycerol could mediate the insulin-induced and exerciseinduced increases in glucose upt...

We describe two cases of myofibrillar myopathies, due to different gene mutations. The first was a girl with cardiomyopathy and sensory axonal neuropathy that underwent cardiac transplantation at 15 years suffers from rotatory scoliosis BAG3 mutation. second is male patient, evident limb-girdle weakness since age 3. Two muscle biopsies were performed ages 3 15, MRI, LDB3 sequence analysis also ...

BACKGROUND Venous stasis caused by immobility is an important risk factor for deep vein thrombosis following surgery and lower limb trauma, in bed-ridden medical patients, and in high-risk long distance air travelers. A safe and convenient method for reducing venous stasis would be useful in patients while in hospital and after discharge during their rehabilitation. SUBJECTS AND METHODS 49 he...

Background Peripheral arterial disease (PAD) is associated with impaired function of the lower extremities, manifested clinically as intermittent claudication or rest pain. Previous studies have suggested that alterations in microcirculation due to a paucity of collateralization may contribute to functional impairment in PAD patients. Therefore, small vessel blood flow at the level of leg muscl...

1. An investigation was carried out in five healthy lean adults to assess whether forearm and calf plethysmography largely reflect muscle blood flow as measured by 133Xe and whether there is substantial variability in the blood flow to muscles located at different sites in the body. 2. Blood flow to forearm and calf flexors and extensors, biceps, triceps and quadriceps was assessed using the 13...

Soft tissue venous malformations of muscles may produce musculoskeletal deformities caused by contracture of the involved muscle. When the venous malformation involves the flexor muscles of the leg, equinus deformity and toe-walking may occur. Three patients with unilateral toe-walking secondary to venous malformation of the calf muscle, showing the classic presentation of this unusual conditio...