BACKGROUND AND PURPOSE Although acute cocaine use has been temporally associated with aneurysmal subarachnoid hemorrhage (aSAH), the prevalence of vasospasm and the clinical outcome of patients experiencing aSAH associated with cocaine exposure are unclear. We have analyzed this patient population in our institution to address these issues. METHODS Between 1992 and 1999, 440 patients presente...

Intracranial aneurysms (IAs) typically develop throughout life, necessitating vigilance in those at high risk in order to avoid aneurysmal subarachnoid hemorrhage (aSAH), the deadly complication of IA. A family history of IA increases personal risk of IA development and rupture: the odds ratio (OR) of subarachnoid hemorrhage (SAH) in persons with one first-degree relative (FDR) is 2.15 while th...

BACKGROUND Grading of patients with aneurysmal subarachnoid hemorrhage (aSAH) is often confounded by seizure, hydrocephalus or sedation and the prediction of prognosis remains difficult. Recently, copeptin has been identified as a serum marker for outcomes in acute ischemic stroke and intracerebral hemorrhage (ICH). We investigated whether copeptin might serve as a marker for severity and progn...

BACKGROUND Aneurysmal subarachnoid hemorrhage (aSAH) survivors commonly exhibit impairment on phonemic and semantic fluency tests; however, it is unclear which of the contributing cognitive processes are compromised in aSAH patients. One method of disentangling these processes is to compare initial word production, which is a rapid, semiautomatic, frontal-executive process, and late phase word ...

The seasonal and diurnal variations in the incidence of hypertension, cerebrovascular accident, coronary heart disease were well documented, but the relation between season and daytime on the onset of aneurysmal subarachnoid hemorrhage (ASAH) was a subject of controversy. In the present study we aimed to evaluate the role of season of year and diurnal changes on the onset of ASAH. The time was ...

Background: Aneurysmal subarachnoid hemorrhage (aSAH) is an acute neurosurgical emergency with a significant fatality rate. In addition to acute brain injury, a considerable part of patients suffering from aSAH develops secondary brain damage such as cerebral vasospasm (CVS). CVS exacerbates the mortality. Therefore, it is urgently needed to find a biomarker, which could predict secondary brain...

Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating form of hemorrhagic stroke with 30-day mortality between 33 and 45%. Delayed cerebral ischemia (DCI) is the chief cause of morbidity and mortality in patients who survive the initial aSAH. DCI accounts for almost 50% of deaths in patients surviving to treatment of the ruptured aneurysm. The mechanisms for brain injury after aSAH and the...

Purpose: To evaluate the effect of hyperbaric oxygen therapy (HBOT) on cognitive impairment after aneurysm subarachnoid hemorrhage (aSAH).
 Methods: The current study was carried out in a regional neurosurgical center Taiyuan, Shanxi Province China from January 2019 to September 2020. A total 150 patients with persistent dysfunction at 3 months aSAH onset were enrolled, which randomly clas...

OBJECTIVE The recent guidelines on management of aneurysmal subarachnoid hemorrhage (aSAH) advise pharmacological thromboprophylaxis (PTP) after aneurysm obliteration. However, no study has addressed the safety of PTP in the aSAH population. Therefore, the aim of this study was to assess the safety of early PTP after aSAH. METHODS Retrospective cohort of aSAH patients admitted between January...

In those who survive the initial impact of aneurysmal subarachnoid hemorrhage (aSAH), delayed ischemic neurological deficit (DIND) is the leading cause of morbidity and mortality. Despite therapeutic advances leading to decreased case fatality rate of 0.9% per year from 1960 to 1992, mainly attributed to improved prevention of rebleeding, the 30-day case fatality rate has remained static, and a...