نتایج جستجو برای: camelidae
تعداد نتایج: 84 فیلتر نتایج به سال:
We analyzed the effects of population density and climatic variables on the rate of population growth in the guanaco ( ), a wild camelid species in Lama guanicoe South America. We used a time series of 36 years (1977-2012) of population sampling in Tierra del Fuego, Chile. Individuals were grouped in three age-classes: newborns, juveniles, and adults; for each year a population transition matri...
Tumor necrosis factor (TNF) plays an important role in chronic inflammatory disorders, such as Rheumatoid Arthritis and Crohn's disease. Recently, monoclonal Camelidae variable heavy-chain domain-only antibodies (V(H)H) were developed to antagonize the action of human TNF (hTNF). Here, we show that hTNF-V(H)H does not interfere with hTNF trimerization, but competes with hTNF for hTNF-receptor b...
The heavy chain fraction present in Camelidae antibodies is so-called nanobodies. They have different characteristics when compared to immunoglobulin G, like more diminutive size, higher affinity, shorter half-life serum, etc. These proteins are codified by B lymphocytes cDNAs and can be produced hosts Escherichia Coli, Pichia Pastoris, plant cells even insect cells. Andean camelids been mainly...
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