نتایج جستجو برای: cancer cytogenetics

تعداد نتایج: 917117  

Journal: :Hematological Oncology 2023

Introduction: The prognosis of chronic lymphocytic leukemia (CLL) varies widely individually. clinical staging systems by Rai and Binet, cytogenetics/FISH, mutational status IGHV have been commonly used as prognostic factors for CLL patients. advent molecular panels next-generation sequencing might provide additional markers to predict the outcome In this study, we evaluate gene mutation profil...

2011
Kevin D. Boyd Fiona M. Ross Brian A. Walker Christopher P. Wardell William J. Tapper Laura Chiecchio GianPaolo Dagrada Zoe J Konn Walter M. Gregory Graham H Jackson J Anthony Child Faith E. Davies Gareth J. Morgan Gareth J Morgan

Supported by: Main financial support for the MRC Myeloma IX clinical trial was from the UK Medical Research Council, with additional funding in the form of unrestricted educational grants from Novartis, Schering Health Care, Chugai, Pharmion, Celgene and Ortho Biotech. The LLR UKMF Cytogenetics group was supported by Leukemia and Lymphoma Research. The Institute of Cancer Research received fina...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه بیرجند - دانشکده علوم 1391

in this thesis, we consider a mathematical model of cancer with completely unknown parameters. we study the stability of critical points which are biologically admissible. then we consider a control on the system and introduce situations at which solutions are attracted to critical points and so the cancer disease has auto healing. the lyapunov stability method is used for estimating the un...

پایان نامه :دانشگاه تربیت معلم - تهران - دانشکده زیست شناسی 1391

بررسی تآثیر کورکومین بر بیان آکواپورین5 در سلول های سرطانی روده بزرگ انسان(ht-29) سرطان روده بزرگ جزو بیماری های خطرناک بوده و از نظر شیوع سومین سرطان شایع و دومین علت مرگ ومیر ناشی از سرطان در جهان محسوب می شود. خطرابتلا به این سرطان تحت تاثیر دو عامل محیطی وفاکتورهای ژنتیکی می باشد. آکواپورین ها، پروتئین های کانال آبی بوده که نقش مهمی را در انتقال آب در بافتهای اندوتلیالی و اپی تلیالی بر عهد...

2006
Jau Hong Kao Jen-Hui Chuang Tsaipei Wang

Automated chromosome classification is an essential task in cytogenetics and has been an important pattern recognition problem. Numerous attempts were made in the past to characterize chromosome to perform clinical and cancer cytogenetics research. It is important to determine optimum features and develop feature extraction schemes for chromosome classification. In this paper we propose novel a...

Journal: :Journal of Medical Genetics 1991

Journal: :International Journal of Hematology 2001

Journal: :American journal of medical genetics 2002
Zhong Chen Avery A Sandberg

The field of molecular cytogenetics has had a great impact on many aspects of medical and basic sciences. During the past 30 years, the application of molecular cytogenetic methodologies has resulted in remarkable advances in the field of cancer genetics and cytogenetics. These advances have led to the establishment of chromosome patterns as diagnostic and prognostic indexes in an array of acut...

Journal: :Stem cell investigation 2016
John Savooji Fouzia Shakil Humayun Islam Delong Liu Karen Seiter

Therapy-related acute myeloid leukemia (AML) is a long term complication of chemotherapy for a variety of cancers. In most cases, the marrow demonstrates high risk cytogenetics and the prognosis is poor. In a minority of patients "good risk" cytogenetics, including t(15;17)(q22;q12), are seen and the patient's prognosis is similar to those who have de novo disease. Currently we present a patien...

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