Background: The herpes simplex virus (HSV) UL41 gene product, virion host shutoff (Vhs) protein, mediates the rapid degradation of both viral and cellular mRNA. This ability suggests that Vhs protein can be used as a suicide gene in cancer gene therapy applications. The recent reports have shown that the degradation of cellular mRNA during herpes simplex infection is selective. RNA containing A...

background most of the cancer patients may suffer from pain; therefore, music therapy -as a noninvasive method- is sometimes used to help reduce the pain of cancer patients. objective to evaluate the effects of music therapy on pain in some patients with cancer. material and methods this semi-experimental study was performed at urmia teaching hospital in 2011. a total number of 60 patients with...

When a cell’s DNA is damaged, the injured cells react by changing from normal to malignant cells, rather than dying or repairing the damage. Metastatic cancer is the deadliest kind of cancer since it refers to cancer that has spread to other parts of the patient’s body. The need for cancer detection techniques that are rapid, non-invasive, and accurate is growing. Cancer diagnosis, monitoring, ...

lentiviral vectors are promising gene delivery tools capable of transducing a variety of dividing and non-dividing cells, including pluripotent stem cells which are refractory for transduction by murine retroviruses. although there is a growing debate on the safety of lentiviral vectors for gene transfer, in particular for those derived from human immunodeficiency viruses, type one (hiv-1) and ...

The most common serious disease today is cancer, which on the rise as a result of kind life we live. Cancer 'Uncontrolled Growth cells' can be prevented if diagnosed earlier stages. numerous internal and external elements producing cancer will determine how it treated. These days, variety treatments, involving gene therapy, chemotherapy, surgery, radiation immunotherapy, etc., are available to ...

despite the major advances in conventional forms of treatment (i.e. surgical techniques, radiotherapy and chemotherapy) and improved survival rates, cancer is still the second leading cause of death in developing countries. one major limitation of cytotoxic drugs and radiation in the treatment of cancer patients is their inability to discriminate between malignant and normal tissues. this in tu...