In vitro and in vivo assessment of safety and efficacy are the essential first steps in developing nanoparticle-based therapeutic systems. However, it is often challenging to use the knowledge gained from in vitro studies to predict the outcome of in vivo studies since the complexity of the in vivo environment, including the existence of flow and a multicellular environment, is often lacking in...

Artificial Intelligence based deep learning techniques using Convolutional Neural Networks (CNNs) can be used to identify oral pre-cancerous (potentially malignant) and cancerous lesions differentiate them from normal mucosa.

Possible effects of aqueous garlic (Allium sativum Linn.) and red clover (Trifolium pratense Linn.) extracts on adenosine deaminase (ADA) activities were investigated in cancerous and non-cancerous human liver tissues and results were compared with those of Fludarabine, a known ADA inhibitor. Ten cancerous and 10 non-cancerous adjacent liver tissues were obtained from patients with metastatic t...

Cypate-octreote peptide analogue conjugate (Cytate) was investigated as a prostate cancer receptor-targeted contrast agent. The absorption and fluorescence spectra of Cytate were ranged in the near-infrared "tissue optical window." Time-resolved investigation of polarization-dependent fluorescence emitted from Cytate in solution as well as in cancerous and normal prostate tissues was conducted....