background: an explosion of research has been done in discovering how human health is affected by environmental factors. i will discuss the impacts of environmental cancer causing factors and how they continue to cause multiple disruptions in cellular networking. some risk factors may not cause cancer. other factors initiate consecutive genetic mutations that would eventually alter the normal p...

background: carcinoma of the fallopian tube is extremely uncommon neoplasm, accounting for only 0.3% of gynecologic cancers. case: a 17-year-old female patient presented with clinical symptoms of right side deep pelvic pain. ultrasound examination reveals right adenxal mass with breakdown suggesting neoplastic lesion or tubo-ovarian abscess. she was diagnosed clinically as tubo-ovarian mass for...

Chronobiotics are a group of drugs, which utilized to modify circadian rhythms targeting clock-associated molecular mechanisms. The clock is known as controller numerous processes in connection with aging. Hypothesis: KL001 and KS15 CRY, affect lifespan, locomotor activity rhythm Drosophila melanogaster. We observed slight (2%, p < 0.001) geroprotective effect on median lifespan (5 µM soluti...

abo blood type antigens are polymorphic, inherited structures presented on the surface of red blood cells. although abo blood group antigens is the most important antigens in transfusion medicine, its main role is not clearly clarified. correlation between abo blood group and susceptibility to certain infectious and non-infectious diseases is a controversial issue. since, lack of blood type ant...

objective: in this study, we aimed at evaluation of the efficacy of hypericum perforatum and flaxseed on hot flash, vaginal atrophy and estrogen-dependent cancers in menopausal women materials and methods: we searched medline, scopus, and the cochrane central register of controlled trials (rct) to explore trials that assessed the effectiveness of h. perforatum and flaxseed on hot flash, vaginal...

More than half of all cancer patients receive radiotherapy as a part of their treatment. With the increasing number of long-term cancer survivors, there is a growing concern about the risk of radiation induced second malignant neoplasm [SMN]. This risk appears to be highest for survivors of childhood cancers. The exact mechanism and dose-response relationship for radiation induced malignancy is...

Cancer survivors face many challenges as a result of their cancer diagnosis and treatment, most importantly the maintenance of physical well-being. Nurses and other health professionals strive to address the needs of cancer survivors, including providing appropriate health-promotion information for a physically active lifestyle. Cancer survivors are at greater risk for recurrence and for develo...

The risk adaptive therapy approach within low risk patients may involve limiting post-transplant IMiD exposure in patients who have a higher potential for SPM development. It may well be that we are looking at the tip of the iceberg in the year 2012 and SPMs may emerge as an important long-term sequela with further follow-up.

BACKGROUND Heightened risks of second cancers have been reported in patients with nonmelanoma cancer of the skin (NMSC), but this association has not been studied in a large, ethnically diverse, multigeographic population. METHODS This cross-sectional study assessed the association of NMSC with another malignancy in the Women's Health Initiative Observational Study, a study that was conducted...