BACKGROUND Reoperation for congenital heart disease may be associated with cardiac or vascular injuries during repeat sternotomy, resulting in increased mortality and/or morbidity rates. The aim of this study was to determine the frequency of these cardiac injuries and the associated outcome. METHODS Between January 2012 and December 2013, 4256 sternotomy procedures were performed at the Pedi...

AIMS The uncertainty surrounding safety of angiotensin receptor blockers (ARBs) increased after publication of experimental and clinical studies which suggested an excess risk of myocardial infarction (MI) in people treated with ARBs. METHODS AND RESULTS We performed a meta-analysis of randomised clinical trials, which compared ARBs with either a placebo or active drugs different from ARBs. O...

Aim: To evaluate the premalignant and malignant lesions of the uterine cervix on light microscopy for apoptosis. To calculate and correlate the apoptotic index (AI), mitotic index (MI) and turnover index of the lesions. Materials and methods: A 2-year retrospective (November 2007 to October 2009) and 1-year prospective study (November 2009 to October 2010). A total of 95 cases of premalignant a...

We previously demonstrated that serotonin (5-HT) and 5-HT2A receptor (5-HT2AR) levels in platelets were up- or down-regulated after myocardial infarction (MI) associated with depression. In this study, we further evaluated the effects of pretreatment with ginseng fruit saponins (GFS) on the expression of 5-HT and 5-HT2AR in MI with or without depression. Eighty Sprague-Dawley (SD) rats were tre...

OBJECTIVE Studies in Western world patients suggest the possible existence of a subgroup of patients with bulimia nervosa (BN) who display multiple problems with impulsivity, such as suicidal attempts. We assessed impulsive behaviors among BN patients in Japan to discuss them crossculturally. METHOD Impulsive behaviors in 64 BN patients were assessed and multi-impulsivity (MI) was defined acc...

Several large-scale studies indicate that factor V Leiden (FVL) is not associated with an increased risk of acute myocardial infarction (MI) in middle-aged or elderly populations.1-7 However, Rosendaal et al8 have hypothesized that FVL might increase the risk of myocardial infarction among women less than 45 years of age, particularly in the subgroup of smokers. Specifically, in a study of 84 w...

Several large-scale studies indicate that factor V Leiden (FVL) is not associated with an increased risk of acute myocardial infarction (MI) in middle-aged or elderly populations.1-7 However, Rosendaal et al8 have hypothesized that FVL might increase the risk of myocardial infarction among women less than 45 years of age, particularly in the subgroup of smokers. Specifically, in a study of 84 w...

The encapsulation of polyoxometalates within the large pores of the Zr(iv) biphenyldicarboxylate UiO-67 metal-organic framework has been achieved, for the first time, by direct solvothermal synthesis. The resulting POM@UiO-67 composite materials were fully characterized by XRPD, IR, MAS NMR, N2 porosimetry measurements and cyclic voltammetry.

Background: Psychocardiological researches have suggested a central role of 5-hydroxytryptamine (5-HT) on psychocardiological mechanism. This study aimed to further explore the central role of 5-HT and pretreatment effects of XinLingWan on rats with myocardial infarction (MI) and/or depression. Methods: Ninety Sprague-Dawley rats were randomly divided into three groups: MI group, depression g...

Mutual information (MI) is useful for detecting statistical independence between random variables, and it has been successfully applied to solving various machine learning problems. Recently, an alternative to MI called squared-loss MI (SMI) was introduced. While ordinary MI is the Kullback–Leibler divergence from the joint distribution to the product of the marginal distributions, SMI is its P...