acute left atrial thrombosis at the site of the resection of the primary cribriform septum is an exceedingly rare and important complication after atrial septal defect (asd) closure with a pericardial or synthetic patch. this case report presents a mobile thrombus noted on the left atrium at the raw surface site of a resected cribriform primary septum that was not caught in the suture line with...

INTRODUCTION The SonR signal has been shown to reflect cardiac contractility. It is recorded with an atrial lead connected to a cardiac resynchronization therapy defibrillator. For the first time, clinical evidence on the use of the SonR signal in the monitoring of the clinical status of heart failure patients implanted with cardiac resynchronization therapy defibrillator are presented through ...

BACKGROUND The only subgroups of patients with heart failure and atrial fibrillation in which the efficacy of cardiac resynchronization therapy has been scientifically proven are patients with indications for right ventricular pacing and patients after atrioventricular junction ablation. However it is unlikely that atrioventricular junction ablation would be a standard procedure in the majority...

OBJECTIVES The purpose of this study was to investigate the factors related to sex-specific outcomes for death and heart failure events in the MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy) trial. BACKGROUND In the MADIT-CRT trial, women seemed to achieve a better result from resynchronization therapy than men. METHODS All 1,820 pat...

A 78-year-old man presents to establish care on his implanted cardiac resynchronization therapy–defibrillator. He has history of permanent atrial fibrillation, ischemic cardiomyopathy, left bundle branch block, and chronic New York Heart Association functional class III congestive heart failure. He had primary prevention cardiac resynchronization therapy–defibrillator implanted 2 years ago and ...

BACKGROUND A reduction in skeletal muscle performance measured by handgrip strength is common in heart failure. No trial has investigated the role of cardiac resynchronization therapy, which leads to improvements in cardiac performance, on the function of skeletal muscle in patients with heart failure. METHODS Nineteen patients were recruited, 18 male, age 69 ± 8 years, New York Heart Associa...

BACKGROUND Electric left ventricular lead position, assessed by the electric delay from the beginning of the QRS complex to the local LV electrogram (QLV), was found in previous studies to be a strong predictor of short-term response to cardiac resynchronization therapy. We hypothesized that suboptimum electric position of the left ventricular lead is associated with an excess of heart failure ...

Cardiac resynchronization therapy is an established treatment modality in heart failure. Though non-response is a serious issue. To address this issue, a good understanding of the electrical activation during underlying intrinsic ventricular activation, biventricular as well as right- and left ventricular pacing is needed. By interpreting the 12-lead electrocardiogram, possible reasons for subo...

UNLABELLED Cardiac resynchronization therapy (CRT) is currently an established device therapy for heart failure (HF) patients. Existing knowledge of implantation techniques, advances in device-based technologies and clinical trial experience have all significantly impacted this evolving therapy in recent years. This review article will address the updated CRT guidelines, and potentially new ind...

BACKGROUND Heart failure is a common, costly, and debilitating illness. Resynchronization of ventricular contraction in patients with heart failure improves ejection fraction. The long-term morbidity and costs associated with such cardiac resynchronization therapy remain unclear. OBJECTIVE To assess the incremental cost-effectiveness of cardiac resynchronization therapy. DESIGN Markov model...