doxorubicin (dox) is an anthracycline antibiotic with broad spectrum anti-tumour activity. its effectiveness has been limited by the occurrence of dose-related myocardial and bone marrow toxicity. as oxidative stress is the main factor in dox-induced cardiotoxicity, we presumed that agents which enhance endogenous antioxidants can prevent dox induced cardiotoxicity. animals received either dox ...

Cardiac myxomas are rare. The clinical diagnosis of an atrial myxoma may occur in an asymptomatic patient but may also present with cardiac failure, syncope, arrythmias, or with vascular evidence of tumour embolisation. The delay in diagnosis from presentation is approximately ten months. We present the case of a 53-year-old woman who attended our Emergency Department with dyspnoea, fatigue and...

We present a case of non-functioning anterior mediastinal paraganglioma in a 61-year-old woman. The tumour was accidentally discovered on a coronary angiography performed in an atypical precordial pain and dyspnea. The coronary angiography showed a vascular tumour in the paraaortic localization irrigated from two branches of coronary arteries. Diagnosis was confirmed by a thoracic tomographic s...