OBJECTIVE To determine whether an impedance threshold device, designed to enhance circulation, would increase acute resuscitation rates for patients in cardiac arrest receiving conventional manual cardiopulmonary resuscitation. DESIGN Prospective, randomized, double-blind, intention-to-treat. SETTING Out-of-hospital trial conducted in the Milwaukee, WI, emergency medical services system. ...

Aerosolized medications are routinely used for the treatment of critically ill patients. This paper reviews aerosol delivery devices with a focus on issues related to their performance in pulmonary critical care. Factors affecting aerosol drug delivery to mechanically ventilated adults and spontaneously breathing patients with artificial airways are reviewed. Device selection, optimum device te...

In this article, the authors explore why medical device innovation has traditionally been geared so thoroughly toward improving performance, with little regard to cost. They argue that the changing incentives in the health care sector and the move to value-based payment models, accelerated by the implementation of the Affordable Care Act, will force device manufacturers to redirect investments ...

INTRODUCTION COPD places a huge clinical and economic burden on the US health care system, with acute exacerbations representing a key driver of direct medical costs. Current treatments, although effective in reducing symptoms and limiting exacerbations, do not adequately target the underlying disease processes that drive exacerbation development. The Aerobika* oscillating positive expiratory p...

This book outlines the underlying pathophysiology of heart failure, summarises standard pharmacological and device therapy, and sets the context of the challenges resulting from an unpredictable course of disease. In easily digestible summaries, this book presents practical advice about how and when to integrate a palliative care approach alongside standard heart failure management, how to comm...

UNLABELLED BACKGROUND Although a device is needed to continuously measure blood glucose levels within an intensive care setting, and several large-scale prospective studies have shown that patients might benefit from intensive insulin, potassium, or glucose therapy during intensive care, no devices are currently available to continuously assess blood glucose levels in critically ill patients...

This book outlines the underlying pathophysiology of heart failure, summarises standard pharmacological and device therapy, and sets the context of the challenges resulting from an unpredictable course of disease. In easily digestible summaries, this book presents practical advice about how and when to integrate a palliative care approach alongside standard heart failure management, how to comm...

This book outlines the underlying pathophysiology of heart failure, summarises standard pharmacological and device therapy, and sets the context of the challenges resulting from an unpredictable course of disease. In easily digestible summaries, this book presents practical advice about how and when to integrate a palliative care approach alongside standard heart failure management, how to comm...

This book outlines the underlying pathophysiology of heart failure, summarises standard pharmacological and device therapy, and sets the context of the challenges resulting from an unpredictable course of disease. In easily digestible summaries, this book presents practical advice about how and when to integrate a palliative care approach alongside standard heart failure management, how to comm...

Improving the quality and safety of intensive care unit (ICU) care in the United States is a significant challenge for the future. Obtaining improvement in systems of care is difficult given the reactionary mode physicians tend to enter when dealing with moment-to-moment crises. It will be important to implement quality and safety measures that are already supported by evidence. Improvement of ...