نتایج جستجو برای: carp pituitary extract cpe

تعداد نتایج: 229165  

Journal: :Endocrine 2003
Ke-ita Tatsumi Susumu Tanaka Toru Takano Shigeyuki Tahara Yoshio Murakami Toshihiro Takao Kozo Hashimoto Yuzuru Kato Akira Teramoto Nobuyuki Amino

Among pituitary disorders having mass effect of the pituitary gland, nonfunctioning pituitary macroadenoma and lymphocytic hypophysitis are difficult to differentiate without histological examination. In order to efficiently distinguish lymphocytic hypophysitis and pituitary tumors, we studied the presence of autoantibodies against prohormone-processing enzymes, prohormone convertase (PC) 1/3, ...

2012
Samuel Takashi Saito Danielle da Silva Trentin Alexandre José Macedo Cristina Pungartnik Grace Gosmann Jaqueline de Deos Silveira Temenouga Nikolova Guecheva João Antonio Pêgas Henriques Martin Brendel

Plant extracts have a long history to be used in folk medicine. Cassia alata extracts are known to exert antibacterial activity but details on compounds and mechanism of action remain poorly explored. We purified and concentrated the aqueous leaf extract of C. alata by reverse phase-solid phase extraction and screened the resulting CaRP extract for antimicrobial activity. CaRP extract exhibited...

2015
Hossein Vaheed S. Mohammad Mousavi S. Abbas Shojaosadati Hasan Galip

Regarding some reported antimicrobial properties of tannins; Zymomonas mobilis was used to obtain ethanol from tannin-reduced carob pod extract (TR-CPE). Culture of 50 ml volume containing 7.5 g sugar at pH 5.5 and 0.03 g bacterial inoculums with shaking at 80 rpm was used. Using response surface methodology (RSM), the maximum ethanol concentration of 5.34 % w/v (higher than that reported earli...

2016
Hoda Alipour Mazandrani SeyedRoholla Javadian Somayeh Bahram

The effect of fennel extract on the quality of silver carp (Hypophthalmicthys molitrix) fillets, and the possible efficacy of liposomal encapsulation in the improvement of its antimicrobial and antioxidant activity during chilled storage (4 + 1°C) of the fillets were examined over a period of 15 days. Silver carp fillets were treated with pure fennel extract (0.3% and 0.5% w/v) and liposomal en...

2015
Ana T.M. Viveiros Antonio C.S. Gonçalves Ariane F. Nascimento Marcelo C. Leal

The effects of reduced doses of OvaprimTM (GnRHa + domperidone) on sperm release of Brycon orbignyanus and Prochilodus lineatus were evaluated. Furthermore, sperm quality was compared among fresh, equilibrated and postthaw samples. Males received a single and reduced dose of OvaprimTM (0.125 or 0.25 ml/kg); control males received pituitary extract (cPE; 3 mg/kg). Fresh sperm was evaluated for v...

2016
Wenzhu Peng Jian Xu Yan Zhang Jianxin Feng Chuanju Dong Likun Jiang Jingyan Feng Baohua Chen Yiwen Gong Lin Chen Peng Xu

High density genetic linkage maps are essential for QTL fine mapping, comparative genomics and high quality genome sequence assembly. In this study, we constructed a high-density and high-resolution genetic linkage map with 28,194 SNP markers on 14,146 distinct loci for common carp based on high-throughput genotyping with the carp 250 K single nucleotide polymorphism (SNP) array in a mapping fa...

2002
Eduardo A. Nillni Weihua Xie Lawrence Mulcahy Vanesa C. Sanchez William C. Wetsel

Cpe mice are obese, diabetic, and infertile. They have a mutation in carboxypeptidase E (CPE), an enzyme that converts prohormone intermediates to bioactive peptides. The Cpe mutation leads to rapid degradation of the enzyme. To test whether pro-thyrotropinreleasing hormone (TRH) conversion to TRH involves CPE, processing was examined in the Cpe mouse. Hypothalamic TRH is depressed by at least ...

2013
Chang-Seon Yoo Sung-Jin Kim

Purpose: To evaluate the mechanism of antioxidant activity of the methanol extract of Codonopsis pilosula. Methods: Anti-oxidative properties were assessed by measuring free radical scavenging activity, nitric oxide (NO) levels, protein oxidation and reducing power, while the mechanism of antioxidative effect of Codonopsis pilosula extract was determined by measuring iNOS and COX-2 expression i...

Journal: :Journal of cell science 2005
Masahiro Hosaka Tsuyoshi Watanabe Yuko Sakai Takeshi Kato Toshiyuki Takeuchi

Secretogranin III (SgIII) and carboxypeptidase E (CPE) bind specifically to cholesterol-rich secretory granule (SG) membranes. We previously showed that SgIII binds chromogranin A (CgA) and targets CgA to the SGs in endocrine cells. We investigated the binding of SgIII and CPE because they frequently localize close to the periphery of SGs, and they bind each other in mouse corticotrope-derived ...

Journal: :The Journal of endocrinology 2004
Suwen Wei Yun Feng Fa-Yun Che Hui Pan Nino Mzhavia Lakshmi A Devi Audra A McKinzie Nancy Levin William G Richards Lloyd D Fricker

ProSAAS is a neuroendocrine peptide precursor that potently inhibits prohormone convertase 1 in vitro. To explore the function of proSAAS and its derived peptides, transgenic mice were created which express proSAAS using the beta-actin promoter. The body weight of transgenic mice was normal until approximately 10-12 weeks, and then increased 30-50% over wild-type littermates. Adult transgenic m...

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