Staphylococcus aureus is the leading cause of skin and soft tissue infections. With emergence antibiotic-resistant bacteria, there an unmet clinical need to develop novel therapies treat The inflammasome components involved in response S. stimulation are well established vitro immune cell cultures. However, formation cells during vivo infections not entirely understood. Therefore, we used mouse...

in this study organotypic adult spinal cord slices were used to investigate whether caspases could participate in the apoptosis of motor neurons. the thoracic region of spinal cord was sliced using a tissue chopper and cultured in a medium for 6h. morphological and biochemical features of apoptosis were assessed by fluorescent staining and terminal deoxynucleotidyl nick end labeling (tunel) met...