Background: Flavonoid-rich foods are beneficially associated with enhancing pulmonary function; however, the protective effects of flavonoids may have an impact on COPD through anti-inflammatory mechanisms. Chronic obstructive disease (COPD) is a prevalent lung high death rate and multiple health problems. Recently, up to 7000 been identified as having anticancer, antioxidant, properties. Vario...

A biologically guided isolation of secondary metabolites from Cousinia alata Schrenk wild plant growing in Akmola region, Kazakhstan, led to the bioactive diterpene grindelic acid (1). Six flavonoids were also isolated and identified as retusine (2), pachipodol (3), jaranol (4), penduletin (5), casticin (6), 5, 7, 3?-trihydroxy-3, 4?-dimethoxyflavone (7). Penduletin (5) showed moderate cytotoxi...