Modelling of the critical micelle concentrations (cmc) using the molecular connectivity indices was performed for a set of 21 cationic gemini surfactants with medium-length spacers. The obtained model contains only the second-order Kier and Hall molecular connectivity index. It is suggested that the index 2χ includes some information about flexibility. The obtained model was used to predict log...

Surfactants are amphipathic substances with lyophobic and lyophilic groups and are critical components in pharmaceutical products. Surfactants have several uses in pharmaceuticals, i) for solubilisation of hydrophobic drugs in aqueous media, ii) as components of emulsions ,iii) surfactant self-assembly vehicles for oral and transdermal drug delivery, iv) as plasticizers in semisolid delivery sy...

in this research, effect of bicomponent mixed surfactant was studied on drop interface coalescence phenomenon in ambient temperature. first basic chemical system was water and toluene and 0.01 gr of sodium dodecyle sulfate (sds) and the second basic system was water and toluene and 0.01 gr of cethyl trimethy amonium bromide (ctab). various weight fractions of second surfactant including 2-hepta...

BACKGROUND Gene transfer using non-viral vectors offers a non-immunogenic and safe method of gene delivery. Cellular uptake and intracellular trafficking of the nanoparticles can impact on the transfection efficiency of these vectors. Therefore, understanding the physicochemical properties that may influence the cellular uptake and the intracellular trafficking can aid the design of more effici...

Cyclodextrins are able to act as host molecules in supramolecular chemistry with applications ranging from pharmaceutics to detergency. Among guest molecules surfactants play an important role with both fundamental and practical applications. The formation of cyclodextrin/surfactant host-guest compounds leads to an increase in the critical micelle concentration and in the solubility of surfacta...

Sodium di(undecenyl) tartarate monomer (SDUT), a vesicle-forming amphiphilic compound possessing two hydrophilic carboxylate head groups and two hydrophobic undecenyl chains gemini surfactant, was prepared and polymerized to form a polymeric gemini surfactant (i.e., poly-SDUT). These anionic surfactant systems with carboxylate (SDUT and poly-SDUT) and sulfate (sodium dodecyl sulfate, SDS) head ...

With the aid of pH variation, direct transformation of a "1-1" cationic-anionic surfactant pair to a "1-2" cationic-anionic surfactant pair was attained in the system of cetyltrimethylammonium bromide and n-decylphosphoric acid. Owing to the transformation of a "1-1" pair to a "1-2" pair, diverse microstructures and peculiar phase behavior in this cationic-anionic surfactant mixture was obtaine...