In order to study and evaluate the indirect immunofluorescent test and the ratio of CD41ymphocytes to CD8 lymphocytes, 97 cases of positive candida cultures were selected from among 400 patients referring to the hospital and suspected of candidiasis. In this study 39% of the patients had an antibody titer less than 1: 160 No significant correlation was seen between canclidiasis and the resu...

Background We investigated whether CD4:CD8 ratio and CD8 count were prognostic for all-cause, AIDS, and non-AIDS mortality in virologically suppressed patients with high CD4 count. Methods We used data from 13 European and North American cohorts of human immunodeficiency virus-infected, antiretroviral therapy (ART)-naive adults who started ART during 1996-2010, who were followed from the date...

BACKGROUND Data on urinary schistosomiasis in Nigeria are mainly epidemological. The knowledge of co-infections of urinary schistosomiasis and other pathogens are important epidemiological tools for the control and health benefits of the rural dwellers. The granulomatous reactions in urinary schistosomiasis is CD4(+) dependent. The CD8(+) is cytotoxic to parasites and it is activated by CD4(+)....

In individuals with human immunodeficiency virus type 1 (HIV-1) infection, CD4:CD8 lymphocyte ratio is often recognized as a quantitative outcome that reflects the critical role of both CD4(+) and CD8(+) T-cells in HIV-1 pathogenesis or disease progression. Our work aimed to first establish the dynamics and clinical relevance of CD4:CD8 ratio in a cohort of native Africans and then to examine i...

the immune responses that develop following epstien-barr virus (ebv) infection are complex and involve both humoral and to a greater extent cell-mediated immune mechanisms. to evaluate the immune response, flow cytometric analysis of the peripheral blood of six patients during the acute phase of ebv infection was performed. this analysis revealed a significant increase in the percentages and th...

multiple sclerosis (ms) is an autoimmune disease of central nervous system. since different types of immune cells are involved in ms pathogenesis, in this study we aimed to evaluate serum levels of several immunological components including soluble cd4 (scd4), scd8, scd163, and immunoglobulins as markers of activity of t-cells, macrophages, and b-cells in different types of ms. serum levels of ...

background: lymphocyte subsets enumeration is considered prominent in the management of primary and acquired immunodeficiency disorders. because of local variations due to race, age, gender, and environmental conditions on lymphocyte subsets, and to improve the accuracy of interpretation of laboratory findings, reference intervals must be determined in every population. objective: to establish ...

Although different factors have been implicated in the CD4/CD8 T-cell ratio recovery in HIV-infected patients who receive effective antiretroviral therapy (ART), limited information exists on the influence of the regimen composition. A longitudinal study carried out in a prospective, single-center cohort of HIV-infected patients. ART regimens including non-nucleoside reverse transcriptase inhib...

BACKGROUND Recent studies reported that the CD4/CD8 T-cell ratio is inversely associated with biomarkers traditionally used to measure immune activation and systemic inflammation in highly active antiretroviral therapy-treated HIV-infected (HIV+) patients. The relation of hepatitis C virus (HCV) coinfection with the CD4/CD8 ratio in HIV+ patients is unknown. METHODS We examined 50,201 CD4/CD8...