نتایج جستجو برای: cecs
تعداد نتایج: 528 فیلتر نتایج به سال:
PURPOSE The corneal endothelium is a target of the aging process. This study was undertaken to reveal the relationship between corneal endothelial cell (CEC) death and the accumulation of advanced glycation end products (AGEs), by investigating the possible mechanism of accumulation of AGE in CECs and its effects on CEC death. METHODS First, the in vivo expression of the receptor was investig...
BACKGROUND This commentary evolved from a workshop sponsored by the National Institute of Environmental Health Sciences titled "Superfund Contaminants: The Next Generation" held in Tucson, Arizona, in August 2009. All the authors were workshop participants. OBJECTIVES Our aim was to initiate a dynamic, adaptable process for identifying contaminants of emerging concern (CECs) that are likely t...
Circulating endothelial cells (CECs) are present in peripheral blood and have been shown to contribute to normal and pathological neovascularization. Antiangiogenic molecules can inhibit neovascularization in tumors and other sites, but their effect on CECs has not yet been determined. We hypothesize that angiogenic factors will increase the number of CECs, and conversely, antiangiogenic treatm...
Purpose: To investigate the predictive value of circulating endothelial cells (CECs) to evaluate the efficacy of transarterial chemoembolization (TACE) and their potential value to guide selection of the time interval of TACE. Materials and methods: 35 hepatocellular carcinoma (HCC) patients suitable for TACE and 10 healthy volunteers were enrolled in this study. Three milliliters of peripheral...
OBJECTIVE Currently the detection of renal vascular lesions (VLS) mainly depends on biopsy examination, and lacks surrogate biomarkers for clinical dynamic evaluation. The aim of this study is to find the correlation between numbers of circulating endothelial cells (CECs) and renal VLS in lupus nephritis (LN). METHODS Thirty LN patients with VLS and 30 LN patients without VLS were recruited. ...
Endothelial contribution to human vascular disorders is difficult to investigate, owing to the paucity of non-invasive methods and of specific endothelial markers . Circulating endothelial cells (CECs) might be used asa surrogate non-invasive marker for the study of vascular alterations. To address this problem, we produced an antibody against the endothelial molecule CD126 (S-Endol) and develo...
BACKGROUND Inflammation is pivotal in atherosclerosis. A key early event in atherosclerosis is endothelial dysfunction. C-reactive protein (CRP), the prototypic marker of inflammation in humans, is a risk marker for cardiovascular disease, and there is mounting evidence to support its role in atherothrombosis. CRP has been shown to promote endothelial dysfunction both in vitro and in vivo. Emer...
BACKGROUND The aim of this study was to investigate the effect of hypoxia on the level of microRNA-18a (miR-18a) and hypoxia-inducible factor 1A (HIF1A) expressed by choroidal endothelial cells through cytological analysis. MATERIAL AND METHODS After culturing choroidal endothelial cells (CECs) under normoxia or hypoxia, microRNAs, expressed in different ways, were screened by using GeneChip ...
Transplantation of ex vivo expanded corneal limbal stem cells (LSCs) has been the main treatment for limbal stem cell deficiency, although the shortage of donor corneal tissues remains a major concern for its wide application. Due to the development of tissue engineering, embryonic stem cells (ESCs)-derived corneal epithelial-like cells (ESC-CECs) become a new direction for this issue. However,...
INTRODUCTION Currently, The nature and scope of Clinical Ethics Protocols (CEPs) in Madrid (Spain) are not well understood. OBJECTIVES The main objective is to describe the features of 'guideline/recommendation' type CEPs that have been or are being developed by existing Clinical Ethics Committees (CECs) in Madrid. Secondary objectives include characterisation of those CECs that have been the...
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