Hemiatrophy of the brain may occur in adults and in old age as a result of degenerative or vascular disorders, but the name is more commonly applied to the congenital or the infantile variety of the condition. It was proposed by Alpers and Dear (1939) that the two varieties be designated secondary and primary respectively. The condition is, however, always secondary in the sense that it is due ...

A rare syndrome, Dyke-Davidoff-Masson Syndrome (DDMS), with a diagnostic conundrum, and the way it was solved is presented. A 13-year-old boy presented with recurrent seizures for the past 10 years. He had been treated with anticonvulsant medication which was satisfactory at first but later the seizures recurred. Recently, the frequency of the seizures increased with preictal dizziness and post...

OBJECTIVE To report a case of progressive facial hemiatrophy with unusual features of contralateral brain atrophy and transcranial Doppler ultrasound evidence of autonomic dysfunction. DESIGN Case report. SETTING A teaching hospital. PATIENT A 63-year-old man who presented with a 10-year history of progressive right-sided facial atrophy and recent facial pain. RESULTS Brain magnetic res...

DESCRIPTION An 18-month-old baby presented with decreased movements of right upper and lower limb since birth. The birth history revealed perinatal insult in the form of delayed cry that was followed by right-sided complex partial seizures. The patient exhibited delayed milestones. There is no history of cyanosis, jaundice or head injury in the neonatal period. At present, the patient is unable...

Dyke-Davidoff-Masson syndrome (DDMS) is a rare, but important cause of drug-resistant seizures. Dyke-Davidoff-Masson syndrome is a constellation of clinical features that consists of hemiparesis, seizure, facial asymmetry, and intellectual disability with distinct neuroimaging features. A 27-year-old lady presented to us with drug-resistant epilepsy, hemiparesis, and intellectual disability tha...

A 54-year-old woman was seen due to weakness and gait difficulty. Physical examination revealed spasticity (Ashworth 2–3), weakness (3/5), hyperactive deep tendon reflexes on the right side, and facial asymmetry. MRI of the brain was consistent with Dyke-Davidoff-Masson Syndrome (DDMS) (figure). DDMS ensues due to an insult to the developing brain, characterized by cerebral hemiatrophy, contral...