Gastrin-releasing peptide (GRP) has been suggested as a novel regulatory peptide in the female reproductive tract but the presence of GRP and GRP mRNA in the non-neurogenic tissue of the cervix has not yet been clarified. In the present study, immunohistochemistry and in situ hybridization were used to reveal the distribution of GRP immunoreactivity and expression of GRP mRNA in the bovine cerv...

Alveolar soft part sarcoma (ASPS) is a tumor of unknown histogenesis, composed of large, epithelioid cells with eosinophilic cytoplasm, having an alveolar pattern. Primary ASPS of uterine cervix is very rare. In this report, we present a 21-aged-old female with primary ASPS in the uterine cervix and discuss the clinicopathological characteristics, immunophenotype, molecular genetic feature and ...

Abnormal looking cervix, or suspicious cervix, is a common clinical condition seen in gynecological practice. Colposcopic examination of the cervix allows differentiation between physiologic changes that occur in response to normal cyclic variations in hormone secretion and a variety of structural and pathological conditions. This article addresses some of these common clinical problems and pro...

Squamous cell carcinoma of endometrium is diagnosed as primary of endometrium if it meets the Fluhmann and Kay criteria [3,4] i.e. absence of concomitant endometrial adenocarcinoma, no continuity between endometrial tumour and stratied squamous epithelium of cervix, no primary carcinoma cervix and if cervix shows carcinoma insitu , there must be no connection between this and independent endom...

Carcinoma cervix was a leading cause of death in women in USA, fifty years ago. Terris and Oalmam and Ratkinhave repeatedly demonstrated a relationship between several parameters of sexual activity and carcinoma cervix. Epidemiological data suggested a sexually transmitted agent as risk factor based on, early age at first intercourse, multiple sexual partners and a male partner with multiple se...

BACKGROUND Cancer of the cervix is the second commonest malignancy in females worldwide and is the leading malignancy among women in Tanzania. Cancer of the cervix has been strongly associated with Human Papilloma Virus (HPV) which is a sexually transmitted disease. However, the role of HIV-1 in the aetiology of cancer of the cervix is less clear. Studies suggest that HPV and HIV-1 infection ar...

Background & Objectives: Tumor diathesis (TD) is defined as granular proteinaceous precipitates on slide surface of cytologic smears. It is found in the background of smears of invasive carcinoma but not in all cases. The aim of present study was to determine the prevalence of TD in cervicovaginal smears from patients with uterine cervix carcinoma. Methods: Cytological smears and histological ...

Abnormal looking cervix, or suspicious cervix, is a common clinical condition seen in gynecological practice. Colposcopic examination of the cervix allows differentiation between physiologic changes that occur in response to normal cyclic variations in hormone secretion and a variety of structural and pathological conditions. This article addresses some of these common clinical problems and pro...

OBJECTIVES The study aims to investigate the efficacy of screening by low-cost technology in down-staging and reduction of mortality due to breast and cervix cancer. METHODS The present trial is a community-based, cluster randomised controlled cohort study on screening for breast and cervix cancers (clinical breast examination and visual inspection of the cervix after application of 4% acetic...

ewing’s sarcoma is a round cell malignancy of bone and soft tissue that occurs predominately in adolescents and young adults.it is an uncommon malignancy, but is recognized as the second most prevalent primary bone tumor worldwide. extraosseous ewing’s sarcoma is extremely rare and can affect the skin, soft tissues, or viscera. prognostic and therapeutic features of ewing’s extraosseous tumors ...