background the prevalence of celiac disease (cd) is remarkably varied in down syndrome(ds)patientscompared with other diseases.  this study aimed to assess celiac disease prevalence in down syndrome children with and without congenital heart defects (chd) and its comparison with controls. materials and methods this case-control study was performed at a single center on 132 participants in three...

background: dyslipidemia is considered an independent risk factor for coronary heart disease (chd). in the present study, we examined lipid profiles and paraoxonase 1 (pon1) activity and atherogenic indexes status and the relationship of pon1 activity by high-density lipoprotein (hdl) and atherogenic indexes in chd patients and healthy people. methods: the aim of the study was to compare pon1, ...

BACKGROUND Hydrogen sulfide (H 2 S) plays a protective role in chronic hemodialysis (CHD) patients. In this study, we further investigate the relationship between H 2 S and conventional protein kinase CβII (cPKCβII) in CHD patients with uremic accelerated atherosclerosis (UAAS). METHODS A total of 30 healthy people, 30 CHD patients without AS and 30 CHD patients with AS (CHD + AS) were studie...

BACKGROUND China will experience an overall growth and aging of its adult population in coming decades. We used a computer model to forecast the future impact of these demographic changes on coronary heart disease (CHD) in China. METHODS The CHD Policy Model is a validated state-transition, computer simulation of CHD on a national scale. China-specific CHD risk factor, incidence, case-fatalit...

BACKGROUND The sex-specific independent effect of diabetes mellitus and established coronary heart disease (CHD) on subsequent CHD mortality is not known. METHODS This is an analysis of pooled data (n = 5243) from the Framingham Heart Study and the Framingham Offspring Study with follow-up of 20 years. At baseline (1971-1975), 134 men and 95 women had diabetes, while 222 men and 129 women had...

INTRODUCTION AND OBJECTIVES Several guidelines on the treatment of cardiovascular risk factors base their recommendations on the assertion that diabetes mellitus (DM) is a coronary heart disease (CHD) or cardiovascular disease (CVD) risk equivalent. To date, no systematic review of studies substantiating this assertion has been carried out. METHODS A systematic search of the PubMed database u...

We use microsimulation to forecast changes in coronary heart disease (CHD) among adults 45 or above over a 20-year time horizon in Los Angeles County (N = 3.4 million), a county with 12 635 CHD deaths in 2010. We simulate individuals' life course and calibrate CHD trends to observed trends in the past. Using the Health Forecasting Community Health Simulation Model, we simulate CHD prevalence an...

Background: Coronary heart disease (CHD) is a major health problem in developed and developing countries. Until now, the death rate due to CHD highest world. Its risk factors include modifiable factors, such as hyperlipidemia, hypertension, diabetes mellitus, obesity, smoking, non-modifiable factors. Purpose: This study aimed determine for incidence of CHD. Methods: employed an unmatched case-c...