In this study, we first demonstrate that the J-integral in classical linear elasticity becomes path-dependent when the solid is subjected to combined electrical, chemical and mechanical loadings. We then construct an electro-chemo-mechanical J-integral that is path-independent under such combined multiple driving forces. Further, we show that this electro-chemo-mechanical J-integral represents ...

A coupled elastoplastic-damage constitutive model taking into account chemo-induced elastoplastic-damage effects for the modeling of coupled chemothermo-hygro-mechanical behavior of concretes at high temperature is proposed in this article. A three-step operator split algorithm for the integration of the rate coupled constitutive equations is developed. Consistent tangent modulus matrices for c...

the effects of combined radiotherapy (rt) and chemotherapy in the severity of cytogenetic alterations expressed as micronucleus (mn) in peripheral blood lymphocytes of patients treated for esophageal cancer was evaluated. to do this, blood was obtained from 23 and 15 esophageal cancer patients scheduled for chemo-radiotherapy and rt alone, respectively, before, during, and after treatment. bloo...

plant-derived natural products are known to have cancer chemo-preventive and chemo-therapeutic properties. plant extracts or their active constituents are used as folk medicine in traditional therapies by 80% of the world population. the aim of the present study was to determine the anti-proliferative potential of fumaria vaillantii extracts on three different cancer cell lines including malign...

The aberrant expression of miRNA has an important function in bladder cancer (BC). Previous studies indicate that LASS2 is involved in the development of sensitivity to chemotherapy in cancer cells. In the present study, the miRNAs related to LASS2 were selected by using miRNA profiling to distinguish chemo-resistant and chemo-sensitive tumor specimens from patients. Higher levels of miR-93 wer...

AIM The aim of the study was to assess the efficacy of chemo-mechanical method for caries removal based on histological analysis and scanning electron microscopy of dentine samples. METHODS Forty-five freshly extracted human deciduous and permanent teeth with dentinal caries were used in this in vitro study. The teeth were allocated to two different technique groups. Chemo- mechanical caries ...

The concept of wireless sensor networks conjures up images of a world of ubiquitous sensing, but it requires a massive increase in the number of sensors available. Although there has been considerable activity in transducer-based 'sensor nets', there have been virtually no corresponding deployments of chemical- or biological-sensing networks - considerable advances in materials science are need...

A smart and reversible chemo-mechanical switch was developed by synthesis of a thermally responsive block copolymer brush poly(N-isopropylacrylamide-co-hexafluoroisopropyl acrylate) (P(NIPAAm-co-HFIPA)) on a capillary plate. With the temperature changing around lower critical solution temperature (LCST), the designed chemo-mechanical switch exhibited excellent "ON-OFF" behavior for water transp...

We report a prototype approach to formulate gold nanoparticle-based X-ray absorbing agents through surface-engineering of a cisplatin pharmacophore with modified polyacrylate. The resulting agents exhibit both chemo-therapeutic potency to cancer cells and Auger-mediated secondary electron emission, showing great potential to improve the therapeutic efficacy of chemo-radiation.