Hepatic lobar atrophy-hypertrophy complex formation is an uncommonly reported sequella of hepatic arterial embolotherapy procedures. Whereas radiation-induced hepatic lobar ablation has been described after intra-arterial therapy with yttrium-90 microspheres, this phenomenon has not been reported after transcatheter arterial chemoembolization. Here, we report a case of prominent hepatic lobar a...

Amongst therapies for unresectable hepatocellular carcinomas, radiofrequency ablation (RFA) and hepatic artery chemoembolization have clinical application either for local tumor destruction or to control tumor progression and recurrence rate. Herein we present a patient with a large hepatocellular carcinoma, chronic hepatitis B and congenital absence of left hepatic lobe treated with hepatic ar...

A case of cerebral lipiodol embolism after transcatheter arterial chemoembolization (TACE) of hepatocellular carcinoma is presented. A 76-year-old man underwent TACE for advanced hepatocellular carcinoma. Immediately after chemoembolization, his level of consciousness deteriorated. Computed tomography revealed deposition of iodized oil in the cerebral cortex, basal ganglia, and thalami. Magneti...

While hepatic arterial chemoembolization is efficacious for a number of malignancies, there is scant data regarding treatment of pancreatic adenocarcinoma. We report a complete radiographic response at one year from diagnosis of metastatic pancreatic carcinoma. Gemcitabine/cisplatin based chemoembolization may be of potential benefit for patients with liver-dominant metastases from pancreatic c...

Primary hepatic carcinoid tumor is rare and poses a challenge for diagnosis and management. We presented a case of primary hepatic carcinoid tumor in a 53-year-old female with a complaint of right upper abdominal pain. Computer tomography scans revealed a hypervascular mass in segment 4 of the liver. An ultrasonography-guided biopsy showed a carcinoid tumor. No other lesions were found by the r...

BACKGROUND According to Barcelona Clinic Liver Cancer classification transarterial chemoembolization is indicated in patients with Hepatocellular Carcinoma in the intermediate stage. Drug-eluting microspheres can absorb and release the chemotherapeutic agent slowly for 14 days after its intra-arterial administration. This type of transarterial chemoembolization approach appears to provide at le...

Pharmacokinetics of chemoembolization with a fibrous collagen carrier was studied in rabbit kidney and porcine liver models. Cisplatin (1 mg/ml) chemoembolization of liver and kidney was compared with i.v. and intraarterial cisplatin infusion. Tissue platinum concentration [Pt] was measured at 2.5 h by atomic absorption spectrometry. Renal platinum retention and Angiostat (collagen for emboliza...

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide, with increasing Transcatheter Arterial Chemoembolization Plus I-Labelled Metuximab versus Transcatheter Arterial Chemoembolization Alone in Intermediate/Advanced Stage Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis Ze-xin Zhu, MD, Ming-heng Liao, MD, Xiao-xue Wang, MD, Ji-wei Huang, P...

background: hepatocellular carcinoma (hcc) is a primary liver cancer that frequently causes mortalities. transarterial chemoembolization (tace) is a new palliative treatment for advanced stages of hcc. in this study, we have assessed the results of tace on a group of iranian patients with advanced hcc treated at imam khomeini general hospital. materials and methods: this was a case series, coho...