Deciding whether to grant an expanded access request for a child whose sibling is enrolled in gene therapy trial involves number of complex factors: considering the best interests child, psychosocial and economic impact on family, concerns obligations researchers. Despite challenges coming substantively fair outcome cases discordant eligibility, creating procedurally decision-making process adj...

Results from 23 studies examining associations between therapeutic relationship variables and treatment outcomes in child and adolescent therapy were reviewed with meta-analytic procedures. Results indicated that the overall strength of the relationship-outcome associations was modest and quite similar to results obtained with adults. This modest association was moderated by 1 substantive facto...

BACKGROUND Longitudinal research is subject to participant attrition. Systemic differences between retained participants and those lost to attrition potentially bias prevalence of outcomes, as well as exposure-outcome associations. This study examines the impact of attrition on the prevalence of child injury outcomes and the association between sociodemographic factors and child injury. METHO...

Differences in infant outcome, predictor variables, and their relationships were explored as a function of maternal employment. Thirty 18-month-olds and their mothers were studied. Child intelligence, attachment security, and dependency were measured, as well as frequency of stressful events in the mother’s life, quality of the parents’ marital relationship, frequency of the mother’s social con...