Background Although the development of effective and safe treatments for prophylaxis of migraine headaches represents an important public health concern, only a few medications have been approved by the specific treatment of patients with migraine. We aimed to compare the efficacy of cinnarizine with propranolol in the prophylaxis of pediatric migraine headache. Materials and Methods  In a Ran...

AIMS To determine the clinical course of childhood abdominal migraine, seven to 10 years after the diagnosis. METHODS A total of 54 children with abdominal migraine were studied; 35 were identified from a population survey carried out on Aberdeen schoolchildren between 1991 and 1993, and 19 from outpatient records of children in the same age group who had attended the Royal Aberdeen Children'...

OBJECTIVE Migraine is a disabling illness that causes absence from school and affects the quality of life. It has been stated that headache may represent an epileptic event. EEG abnormality is a prominent finding in children with migraine. The aim of this study was to evaluate EEG abnormalities in children with migraine. MATERIALS & METHODS Two-hundred twenty-eight children were enrolled into...

how to cite this article: fayyazi a, khajeh a, ghazavi a, sangestani m. omega 3 in childhood migraines; a double blind randomized clinical trial. iran j child neurol. winter 2016; 10(1):9-13. abstract objective the effect of using omega-3 to prevent migraine attacks has been raised in recent studies. the majority of these studies have been conducted in adults. conversely, other studies have yet...

Studies have shown fluctuations of cytokine levels in patients with migraine headaches; however, further studies are needed to verify these results. Our previous studies suggest increased levels of pro-inflammatory cytokines, such as IL-1alpha, sTNF-RI and TNF-alpha, in children with migraine headaches. In this study, we analyzed anti-inflammatory cytokines interleukin-4 (IL-4), interleukin-10 ...

INTRODUCTION Attention Deficit Hyperactivity Disorder (ADHD) is a common comorbid condition in children with epilepsy and migraine. Treatment of ADHD in children with epilepsy or migraine is essential but clinicians may overlook symptoms of ADHD and avoid appropriate use of medications that may reduce symptoms of ADHD without compromising treatment of epilepsy or migraine. Areas covered: PubMed...

Obesity and headache are two highly prevalent diseases both in adults and children and they are associated with a strong personal and social impact. Many studies suggest that obesity is comorbid with headache in general, and migraine in particular and obesity seems to be a risk factor for migraine progression and for migraine frequency both in adults and in children. Research shows that there a...

INTRODUCTION Migraine is considered to be a multifactorial, complex disease. Various genetic and environmental factors contribute to the manifestation of this disease. The aim of this study was to determine whether polymorphisms in the tumour necrosis factor (TNF) region are associated with the risk of migraine. We examined the association between 6 single nucleotide polymorphisms in the coding...

how to cite this article: ashrafi mr, najafi z, shafiei m, heidari k, togha m. cinnarizinev ersus topiramate in prophylaxis of migraines among children and adolescents: a randomized, double-blind clinical trial. iran j child neurol. 2014 autumn;8(4): 18-27.   abstract objective migraines, a common health problem in children and adolescents, still do not have an fda approved preventive treatment...

Headaches in children and adolescents are still under-diagnosed. 75% of children are affected by primary headache by the age of 15 with 28% fitting the ICHD2 criteria of migraine. Migraine is considered a chronic disorder that can severely impact a child's daily activities, including schooling and socializing. Early recognition and aggressive therapy, with acute and prophylactic treatments, as ...