The seroprevalences of Chlamydia trachomatis and rubella IgG antibodies were measured in women with full-term deliveries (n = 198) and with abortion (n = 79) in a hospital in Baghdad city, Iraq. Positive rubella antibody titres were found in 42.9% of mothers with full-term deliveries and 34.2% with abortion. C. trachomatis infection was found in 13.6% of mothers with full-term deliveries and 6....

The direct immunofluorescence assay (DFA) was compared with culture for test-of-cure analysis for Chlamydia trachomatis in patients 7 to 10 days after antimicrobial therapy was given. DFA test-of-cure results correlated with culture results in 79.5% of 39 patients. Of DFA-negative patients, 97% had negative cultures. Six of seven patients with borderline DFA results had negative culture results.

A 36-year-old Japanese woman complained of right hypochondralgia followed by ascites. Paracentesis showed a turbid, straw-colored sterile exudate. Computed tomography and magnetic resonance imaging of the abdomen revealed a left periuteric mass and ascites. The mass and ascites spontaneously regressed within a month with no specific treatment. Later, after the patient had been discharged from h...

Background: Chlamydia (C.) trachomatis is an obligate intracellular gram-negative pathogen affecting over 600 million people worldwide with 92 million new cases occurring globally each year. Genital C. trachomatis infection has been recognized as the most common cause of pelvic inflammatory disease leading to severe tubal damage, ectopic pregnancy, hydrosalpinx and infertility. However, the mec...

OBJECTIVE To determine whether the humoral anti-chlamydia antibody response might be related to the ineffective bacterial elimination seen in patients with Chlamydia trachomatis reactive arthritis, particularly in men, who have a higher prevalence of the disease than women. METHODS The number and specificity of the antibody responses to 27 different C trachomatis antigens were determined by w...

PURPOSE Chlamydia trachomatis is the leading infectious cause of blindness. The goal of the current study was to search for biomarkers associated with C. trachomatis-induced ocular pathologies. METHODS We used a whole genome scale proteome array to systematically profile antigen specificities of antibody responses to C. trachomatis infection in individuals from trachoma-endemic communities wi...

BACKGROUND We evaluated whether measuring chlamydia genus- and species-specific immunoglobulin (Ig) G antibodies might improve the predictive value of C. trachomatis antibody testing (CAT) in screening for distal tubal pathology (DTP). METHODS Serum of 313 subfertile women was tested for the presence of species-specific antibodies to C. trachomatis, C. pneumoniae and C. psittaci and genus-spe...

Abstract C. trachomatis infections in women may cause pelvic inflammatory disease, chronic pain, and infertility. In the mouse model, genital Chlamydia disseminates systemically to infect spleen. Removal of spleen (splenectomy) abrogates hydrosalpinx pathology female reproductive tract (FRT), although it does not affect FRT clearance. Ascension upper (uteri, ovaries, oviducts) is critical for d...