A case of intrahepatic cholestatic jaundice following warfarin therapy is described. The patient made a complete recovery on withdrawal on the drug.

Reports to the Committee on Safety of Medicines show that skin reactions are the commonest adverse reaction to trimethoprim; the committee has had a few reports of cholestatic jaundice due to trimethoprim and to trimethoprim-sulphamethoxazole. Manufacturers of trimethoprim (Duphar) have received four reports of hepatic reactions: hepatitis (two), jaundice (one), and cholestatic jaundice (one). ...

OBJECTIVE To report an infrequent case of Stauffer's Syndrome with jaundice as a paraneoplastic syndrome of a metastatic renal cancer. METHODS We describe the set up of cholestatic jaundice without neoplastic liver infiltration in a patient with a metastatic renal cell carcinoma, which turned back with surgery and systemic treatment. RESULTS Proper treatment of baseline disease enables turn...

Introduction Obstructive jaundice due to carcinoma of the pancreas is uncommon in patients under the age of 40, where jaundice is usually a sequel to viral hepatitis, drug ingestion, alcohol or gallstone disease. The appearance of extra-hepatic obstruction due to carcinoma during the cholestatic phase of viral hepatitis is unusual.

In this prospective study, antithrombin III, plasminogen and alpha 2 antiplasmin which are synthetised by the liver were measured and compared with the Normotest, Thrombotest and fibrinogen concentrations in 92 consecutive jaundiced patients. Antithrombin III appeared to be the most discriminant coagulation test in differentiating hepatocellular from cholestatic jaundice. A high correlation was...

Cholestatic jaundice in early infancy is a complex diagnostic problem. Misdiagnosis of cholestasis as physiologic jaundice delays the identification of severe liver diseases. In the majority of infants, prolonged physiologic jaundice represent benign cases of breast milk jaundice, but few among them are masked and caused by neonatal cholestasis (NC) that requires a prompt diagnosis and treatmen...