Non-Hodgkin lymphoma (NHL) is one of the masquerade syndromes of malignant melanoma that can occur with two main patterns of presentations in the eye: metastatic involvement of uveal tract, and primary involvement of retina. We report ophthalmic, imaging and histopathological findings in the first case diagnosed as primary choroidal NHL without central nervous system or systemic involvement. A ...

Choroidal melanoma is the most common primary intraocular malignancy in adults. Herein, authors report two cases of subretinal hemorrhage associated with it. The first case presented a large choroidal mass hemorrhage, no history trauma and diagnosis on ultrasound. second was initially diagnosed retinal detachment but during surgery pigmented observed, starting to bleed after scleral depression....

Introduction: Melanomas are malignant neoplasms that occur in various anatomical sites, including the eye. Ocular melanomas account for 5% of all and mainly described Caucasian older individuals. This study describes clinical pathological characteristics uveal (choroid) melanoma a patient. Case report: A 41-year-old female patient, brown eyes, without history ophthalmological diseases or family...

Choroidal melanoma is the commonest adult primary intraocular tumour,1 and usual sites of secondary spread are to liver, bone and lung. Although delayed recurrence of ipsilateral orbital melanoma is well documented, metastasis to the contralateral orbit is a rarely encountered phenomenon. We describe a case of metastatic spread to the contralateral orbit in a patient 12 years after proton beam ...

BACKGROUND Choroidal malignant melanoma is a rare intraocular cancer in Asian Indian population. There is a paucity of data from our population comparing iodine 125 (I-125) brachytherapy and enucleation. AIM This study aims to compare two groups of choroidal melanoma patients treated with either I-125 brachytherapy or enucleation in the Asian Indian population. OBJECTIVES To evaluate the lo...

OBJECTIVE To report two cases of concomitant choroidal melanoma and intraocular non-Hodgkin lymphoma in two patients. DESIGN Case report. PARTICIPANTS Two patients with yellow creamy infiltrates in fundo. INTERVENTION Both patients had a complete ophthalmologic evaluation and histology was obtained after enucleation of the affected eye. MAIN OUTCOME MEASURES Histology findings of the en...

Choroidal osteomas are benign, juxtapapillary, choroidal tumors that mandate no treatment. They occur predominantly in young (median age, 20 years) females (90%). While ophthalmoscopy and fluorescein angiography reveal suggestive ophthalmic findings, echography, plain radiography, and especially computed tomography (CT) are important in establishing the correct diagnosis. These lesions may be c...

Purpose We investigated the application of contrast-enhanced ultrasound (CEUS) to quantify vascular perfusion in two animal models of choroidal melanoma. Methods B16F10 and choroidal melanoma cell line (OCM1) melanoma xenografts were implanted into the cyclodialysis cleft of rabbits' right eyes. Fundus photography, indocyanine green angiography (ICGA), B-mode ultrasound, and CEUS were used to...

A 52-year-old woman was found to have a small juxtapapillary pigmented lesion in the choroid of the left eye. This lesion remained clinically stationary for one year, but subsequent growth prompted enucleation of the eye. The tumour was diagnosed histologically as a choroidal malignant melanoma of mixed cell type. Approximately 52 months later the patient developed proptosis of the contralatera...

BACKGROUND The Collaborative Ocular Melanoma Study (COMS) is a 3-arm study that includes two multicenter randomized clinical trials designed to compare the effectiveness of brachytherapy to enucleation for treatment of medium-size choroidal melanomas, and the effectiveness of enucleation with and without preoperative external-beam radiotherapy for large choroidal melanomas. The third arm is an ...