emerging new medications in the treatment of hbv produces hope and promises for curing of hbv. over the past decade, the development of oral nucleoside/nucleotide analogs (nas) with favorable potencies and tolerabilities has led to substantial advances in chronic hepatitis b (chb) therapy. the oral anti-hbv agents currently approved are lamivudine, adefovir dipivoxil , entecavir , telbivudine, ...

background beta-2 microglobulin (b2m) is considered as a surrogate marker for middle molecule uremic toxins and a key component in dialysis-related amyloidosis. however, few studies have evaluated role of b2m in patients with chronic kidney disease (ckd). objectives the purpose of this study was to evaluate the association of plasma b2m level with some metabolic and cardiac performance factors ...

introduction: invasive fungal sinusitis, though considered to be rare entity, is nowadays frequently encountered, not only in immunocompromised patients but also in immunocompetent patients. the changing prevalence towards immunocompetent hosts is due to the indiscriminate usage of broad spectrum antibiotics, steroids, and immunosuppressive drugs. diagnosing invasive fungal sinusitis should not...

background and objective: chronic rhinosinusitis (crs) is one of the most common chronic diseases. in the past decades, there has been an increase in fungal infections of sinuses and fungal rhinosinusitis (frs) has been diagnosed more frequently. knowing the fungal flora and its prevalence in crs patients will allow a better understanding of this disease, permitting a correct diagnosis, treatme...

background: the purpose of this study was to test the hypothesis that the addition of buspirone, a partial agonist of 5ht1a receptor, to ongoing treatment with typical antipsychotics would improve the positive and negative symptoms in patients with chronic schizophrenia. materials and methods: in this study, 50 patients including 40 male and 10 female were recruited with chronic schizophrenia w...

background and objective: non-specific granulomatous prostatitis is an uncommon diffuse inflammatory condition of the prostate. it is important because it may be mistaken for prostatic carcinoma. the aim of the study was to determine the prevalence of non-specific granulomatous prostatitis (nsgp) and comparing the results of transrectal ultrasonography, serum prostate specific antigen (psa) and...

context resilience can be seen as an adaption to stress, such as that caused by health problems or disease, that attenuates the negative effects of stress. the present research performed a systematic review and meta-analysis to study resilience scores among adults diagnosed with chronic physical diseases. evidence acquisition electronic databases, including persian language (scientific informat...

introduction chronic diarrhea of infancy is a heterogeneous syndrome that includes several diseases with different etiologies. the aim of this study was investigating chronic diarrhea, its etiologies, clinical features and outcomes in infancy.materials and methods retrospective study investigating infants hospitalized in the gastroenterology department of tehran tertiary care center.the main de...