BACKGROUND: With chronic infection, hepatitis C virus (HCV) RNA can be detected in B cells and associated with B-cell disorders, but these are not well defined. METHODS: The relationship between HCV infection and lymphocyte subpopulations was evaluated rigorously in 120 asymptomatic hemophilic patients, randomly selected from a prospective cohort study. CD4+ T cells, CD8+ T cells, CD19+ B cells...

BACKGROUND Co-infection with hepatitis C virus (HCV) and/or human immunodeficiency virus (HIV) in patients with chronic hepatitis B virus (HBV) infection can alter the course of the disease. OBJECTIVES In this study, we investigated the frequency of HIV and/or HCV co-infection in chronic HBV patients and related risk factors in acquiring the HCV and or HIV co-infectionit. PATIENTS AND METHO...

background and aims: viral hepatitis is a global health problem with a high mortality rate. recently, a new flavi-like virus, provisionally named hepatitis g virus (hgv), has been described. hgv does not induce an immune response that is consistently detectable by using recombinant proteins from prokaryotic expression, therefore studies have been conducted by using polymerase chain reaction (pc...

abstract background: combination therapy with interferon and ribavirin is the most effective treatment for chronic hepatitis c today. the aim of this study was to evaluate the efficacy and safety of thrice-weekly heberon (interferon alfa-2b) in combination with ribavirin as first -line treatment of chronic hepatitis c. methods: a total of97 treatment-naive patients received heberon three millio...

Background and Aims: Hepatitis C virus (HCV) can cause hepatocellular carcinoma (HCC) in a significant proportion (≈ 20 %) of individuals with chronic HCV infection (CHC). Currently, CHC is treated with peginterferon and ribavirin, which depending on genotype approximately 50 to 70% of patients are cured. The so-called “extrahepatic HCV infection” or viral replication in regio...

conclusions our data show that not only general health and physical activity were preserved but also health perception may be better among hd patients with viral hepatitis. background there are surprisingly a few studies that evaluate the impact of chronic viral hepatitis, which is common in hd (hemodialysis) patients, on hrqol (health related quality of life). objectives we conducted a study t...

Liver biopsy is historically the gold standard for liver fibrosis assessment of chronic hepatitis C patients. However, with introduction and validation noninvasive tests (NITs) to evaluate advanced fibrosis, direct-acting antiviral agents treatment virus (HCV), role NITs have become even more complex. There now need longitudinal monitoring elucidation cutoff values prediction liver-related comp...

Abstract Hepatic steatosis is a frequent pathological finding in patients with chronic viral C infection (HCV) and can be independently associated increased alcohol consumption, type 2 diabetes, obesity hyperlipidemia. All these factors lead to the development of hepatic HCV. There are several noninvasive techniques scores used for diagnosing quantifying liver steatosis. Successful eradication ...

conclusions snps within the ccr5 gene should be considered as an important factor used in combination with other host gene snps when developing a mathematical model for anticipating response to hcv therapy. background chronic hepatitis c virus (hcv) infection is a globally serious public health issue. objectives in this study, we investigated cc chemokine receptor 5 (ccr5-59029) polymorphism wh...