نتایج جستجو برای: chronic itp

تعداد نتایج: 499127  

Journal: :Annals of clinical and laboratory science 1988
M Szal N Blumberg

Studies are reported pertaining to platelet-associated IgG (PAIgG) and IgM (PAIgM) in patients with thrombocytopenias considered possibly immune-mediated on clinical grounds. Approximately 14 percent of all patients with these disorders had elevated PAIgM but normal levels of PAIgG. Of patients with classic autoimmune thrombocytopenia (ITP), there was a trend toward more frequently normal level...

Journal: :iranian journal of allergy, asthma and immunology 0
ramyar asghar department of pediatrics, division of hematology, children medical center hospital, tehran universit aghamohammadi asghar moazzami kasra rezaei nima yeganeh mehdi pouladi taher cheraghi2

common variable immunodeficiency (cvid) is a heterogeneous group of disorders characterized by hypogammaglobulinemia and an increased susceptibility to recurrent infections as well as autoimmunity and malignancies. idiopathic thrombocytopenic purpura (itp) and autoimmune hemolytic anemia (aiha) are two autoimmune disorders which may be seen in association with cvid. among 85 cvid patients, seve...

2015
Rojin Park

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Chronic immune thrombocytopenia (ITP) is an auto-immune disease characterized by immune-mediated platelet destruction and reduced platelet production caused by antiplatelet autoantibodies, leading to a marked decrease in platelet count and rarely life-threat...

Journal: :Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi 2007
Kuan-Sheng Wu Chih-Cheng Hsiao Hong-Ren Yu Eng-Yen Huang Wan-Li Mai Jiunn-Ming Sheen

BACKGROUND Several studies showed some chronic idiopathic thrombocytopenic purpura (ITP) patients with complete platelet recovery after Helicobacter pylori (H. pylori) eradication and cited the cause of persistent thrombocytopenia as inability to eradicate H. pylori. So we studied H. pylori infection status in pediatric ITP patients at diagnosis and address whether such infection played a role ...

Masoud Asadi-Khiavi, Minoosh Moghimi, Reza Mansouri, Saeed Razavi-Dizaji, Saeideh Mazloomzadeh, Sahar Baba Ali, Sattar Jafari, Shahrbanoo Keyhanian, Yousef Mortazavi, Zahra Ghadimi,

Background and Objective: Different studies have investigated the link between helicobacter pylori and extra digestive diseases such as idiopathic thrombocytopenic purpura. However, the relationship between ITP and H pylori is less clear. Most of the studies have focused on H pylori eradication in chronic ITP, so we focused on the effect of H pylori eradication on chronicity of ITP in adult pat...

2015
Bedrettin Yıldızeli Mehmed Yanartaş Sibel Keskin Işık Atagündüz Ece Altınay

Immune thrombocytopenic purpura (ITP) patients are at high risk for bleeding complications regarding surgeries involving cardiopulmonary bypass. We report an ITP patient with chronic thromboembolic pulmonary hypertension who underwent uncomplicated pulmonary endarterectomy with receiving postoperative intravenous immunoglobulin (IVIG) therapy. The positive outcome of this case may suggest that ...

2016
Hyoung Soo Choi Mi Hong Ji Sung Jin Kim Hyo Seop Ahn

BACKGROUND Childhood immune thrombocytopenic purpura (ITP) is a common acquired bleeding disorder. Even though most children recover, either spontaneously or with therapy, 10-20% of newly diagnosed ITP cases have a chronic course beyond 12 months. This study evaluated whether clinical and laboratory findings can predict the response to intravenous immunoglobulin (IVIG) and progression to persis...

Journal: :British journal of haematology 2009
James N George Susan D Mathias Ronald S Go Matthew Guo David H Henry Roger Lyons Robert L Redner Lawrence Rice Martin R Schipperus

Health-related quality of life (HRQoL) is a major concern for adults with chronic immune thrombocytopenic purpura (ITP) due to the symptoms associated with the disease and its treatment. This study utilized the ITP-patient assessment questionnaire (ITP-PAQ), a specialized HRQoL questionnaire for ITP, to investigate the humanistic burden of ITP and the impact of romiplostim therapy on HRQoL in t...

2010
Andreas Rank Oliver Weigert Helmut Ostermann

Traditionally, anti-platelet autoantibodies accelerating platelet clearance from the peripheral circulation have been recognized as the primary pathopysiological mechanism in chronic immune thrombocytopenia (ITP). Recently, increasing evidence supports the co-existence of insufficient megakaryopoiesis. Inadequate low thrombopoietin (TPO) levels are associated with insufficient proliferation and...

2010
Meaghan Khan Joseph Mikhael

Immune thrombocytopenic purpura (ITP) is an autoimmune disorder that is characterized by antibody-mediated platelet destruction and decreased platelet production. ITP and its treatments have been recognized to cause diminished quality of life in those afflicted with this illness on levels comparable to other chronic diseases. The disease can be self-limiting, but in adults it often is a chronic...

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