adenocarcinoma in situ is one of the premalignant lesions of the cervix and its incidence is believed to be increasing while the pathogenesis of the disease is not clearly understood. management of adenocarcinoma in situ (ais) unlike carcinoma in situ (cis) has not been clearly described in the current literature. here we describe conservative management and serial  olposcopy of two pregnant wo...

Background: Differentiating oligodendrocyte precursor cells (OPCs) into oligodendrocytes could be improved by inhibiting signaling pathways such as Wnt and Notch. 9-cis-retinoic acid (9-cis-RA) and 1,25-dihydroxyvitamin D3 (1,25[OH]2D3) can ameliorate oligodendrogenesis. We investigated whether they could increase oligodendrogenesis by inhibiting the Wnt and Notch signaling pathways.Methods: Co...

epoxyalcohols are useful intermediates in complex organic synthesis, and recently they have been recognized as versatile intermediates for synthesis of natural products. the treatments of cis and trans 2-(1-cyclohexenyl) cyclohexanol, separately with paranirto perbenzoic acid gave the corresponding 2-(1- cyclohexenyl) cyclohexanol oxide. on the other hand, 2-cyclohexylidene cyclohexanol oxide w...

Syntheses of bischalcogenides and Mo(0) W(0) complexes bis(2-diphenylphosphinoimidazol-1-yl)methane (1), bis(5-diphenylphosphinopyrazol-1-yl)methane (2) bis(5-diphenylphosphino-1,2,4-triazol-1-yl)methane (3) are described. The reactions 1-3 with aq. H2O2 or elemental sulfur afforded corresponding bis(chalcogenide) derivatives 4-6 7, respectively. [M(NC5H11)2(CO)4] (M = Mo, W) resulted in the fo...