We apply novel atomistic simulations based on potential energy surface exploration to investigate the constant force-induced unfolding of ubiquitin. At the experimentally-studied force clamping level of 100 pN, we find a new unfolding mechanism starting with the detachment between β5 and β3 involving the binding site of ubiquitin, the Ile44 residue. This new unfolding pathway leads to the disco...

Electrowetting on dielectric-coated electrodes involves two independently observable phenomena: (i) the well-known voltage dependence of the apparent contact angle and (ii) a central electromechanical force that can be exploited to move and manipulate small liquid volumes on a substrate. The electromechanical force does not depend upon field-mediated changes of the contact angle; it is operativ...

Abstract The operational accuracy of the dosing system potato planting machine influences plant spacing, and indirectly crop yield. operating depends on design system, its kinematics forces acting tubers. This dissertation presents force vectors in guided clamping finger type their spatial motion during process. Examination reveals improved possibilities tuber fixation.