Actas Dermosifiliogr. 2009;100:235-48 244 incidence in areas exposed to sunlight in patients with a history of basal or squamous cell carcinoma; b) other carcinogens—frequent occurrence in areas of irradiation, erythema ab igne, or following chronic exposure to arsenic; c) immunosuppression—from treatment in a liver or heart transplant setting or rheumatic diseases; and in patients with hematol...

At the NCCN 2023 Annual Conference, experts reviewed clinical data on established therapies for patients with metastatic renal cell carcinoma and discussed strategies to effectively manage both clear non–clear tumor histologies in setting of advanced stages. Depicted through 3 separate case studies, they strategized selection optimal first-line subsequent-line based individual study characteris...

•Primary vaginal clear cell adenocarcinoma (PVCCA) coexists with urinary tract anomalies without exposure to diethylstilbestrol in some cases.•PVCCA in our case showed genetic alterations of well-known cancer related genes, including a mutation of PIK3CA.•The genetic profile suggests that the carcinogenesis of PVCCA might have elements common with that of OCCA.

We read the publication on “Serum tissue factor (TF) as a biomarker for renal clear cell carcinoma”. Silva et al. noted that “TF appears to be a useful serum marker for the presence of clear cell RCC (1)”. Indeed, to conclude that TF is an important biomarker, there should be a complete evaluation on this diagnostic test. Sensitivity and specificity should be studied. Also, some confounding med...

introduction: metastatic lesions of the oral cavity are extremely rare, accounting for approximately 1% of all malignant oral tumors. the most common primary sources of metastatic tumors in the oral region are, from the most to the least common, the breast, lung, kidney, bone, and colon. renal cell carcinoma accounts for nearly 3% of all adult malignancies. it usually metastasizes to the lungs,...

Thyroid gland metastatic tumors are rare in clinical practice. Clear cell RCC is one of common metastatic tumors to thyroid. We here reported a case of incidentally found clear cell renal carcinoma metastasis to the thyroid gland 3 years after nephrectomy, in the thyroidectomy procedure performed for the patient due to the thyroid enlargement caused by multinodular goiter. A 65-year-old Iranian...

a case is reported with clear cell sarcoma (ccs) of the hand. early diagnosis of clear cell sarcoma is always difficult due to its slow growing nature, benign clinical appearance, lack of pigmentation in most cases, and relatively young age of patients which make it to clinically appear as a benign soft tissue tumor. we report a case of clear cell sarcoma of hand in a 56 year old male with a no...