Cervical cancer as one of the major malignant tumors seriously threatens women's health. More than 270,000 women die cervical each year. Warangalone is an isoflavone compound isolated from Cudrania tricuspidata with excellent antitumor activity. In this research, we investigated molecular mechanism warangalone-induced apoptosis in HeLa cells. The results show that warangalone can selectively an...

Haematologica vol. 85(4):April 2000 3. Magrath IT, Adde M, Shad A, Witts RE, Horak ID. Results in adults with small non-cleaved cell lymphoma treated with a short duration intensive chemotherapy protocol also used in paediatric patients [abstract]. Proceedings ASCO 1994; 1252. 4. Waits TM, Greco FA, Greer JP, et al. Effective therapy for poor-prognosis non-Hodgkin’s lymphoma with 8 weeks of hig...

OBJECTIVE To observe the frequency of histological subtypes of childhood non-Hodgkin's lymphoma and its immunohistochemical profile. SETTING All cases of non-Hodgkin's lymphoma diagnosed in children (< 15 years) in the section of histopathology at the Aga Khan University Hospital Karachi during the period of three years. METHODS These consecutive cases were evaluated on H&E stained sections...

A 75-year-old male was pointed out the right submandibular swelling followed by the left pre-auricular swelling, about half-year apart. Parenchyma of the left parotid gland was infiltrated by lymphoid growth, and the right submaxillary gland had a discrete lymphoid growth at a pole of the gland. Inside and outside these lymphoid growths, lymphocytes infiltrated between ducts, acini, adipose tis...

Peripheral T-cell lymphomas are a group of heterogeneous disorders and according to WHO classification, are categorized into nodal and extranodal forms. NK/T-cell lymphoma, nasal type, is a subtype of extranodal peripheral T-cell lymphoma and commonly presents as a midfacial destructive lesion. This disorder is more prevalent in Asia and South America and has a strong association with Epstein B...

The use of functional foods and their bioactive components is receiving increasing attention as a complementary alternative therapy for chronic ulcerative colitis (UC). This study explored the protective effect mechanisms Eckol, seaweed-derived phlorotannin, on dextran sodium sulfate (DSS)-induced UC in mice. Eckol (0.5–1.0 mg/kg) reduced DSS-enhanced disease activity indexes, alleviated shorte...

oral cavity t-cell lymphoma occurs rarely. this case report describes a patient with such a tumor. the case was a 75 years old man presented with a painless swelling on his hard palate mucosa. he had suffered from nose- bleeding and nasal obstruction. pathology revealed the presence of a t-cell lymphoma tumor in the palate. though rare, the signs and symptoms of the case suggest that t-cell lym...

A case of feline multicentric lymphoma is reported in an 8-year-old male cat weighing 4.7 kg. At the time of the clinical consultation the animal presented weight loss, anorexia and generalised lymphadenomegaly. After careful clinical observation and a detailed laboratory workup, the diagnosis of small cleaved cell lymphoma was established. It was classified as a stage III b multicentric lympho...

we report a case of a. naeslundii bacteremia in an 11 year-old boy with persistent fever for two weeks prior hospital admission. he was finally diagnosed with malignant t cell lymphoma. isolation of this bacterium from the blood culture of our patient can serve as an important warning indicating that incuriosity about fastidious and not easily grown bacteria isolated from clinical samples may l...

We explored two cases of CD20-positive cytotoxic T cell lymphoma, a gastric lymphoma and an intestinal lymphoma. Neoplastic cells of the gastric lesion, possessing small cleaved-like nuclei with dense nuclear chromatin, infiltrated the mucosa in association with disappearance of the gastric glands. Neoplastic cells of the intestinal case had large, round nuclei with conspicuous nucleoli, with u...