Introduction: Cleft lip and palate, the most common developmental deformity, is seen worldwide and the etiology involves a combination of genetic and environmental factors. The purpose of this study was to determine the maternal risk factors associated with the development of cleft lip and cleft palate. Materials and Methods: We conducted a case control study at the Women’s Hospital in Culiacan...

STATEMENT OF THE PROBLEM Peripheral and central giant cell granuloma are two common benign lesions of the oral cavity. In spite of histopathological similarities, they have different clinical behaviors. Cathepsin D is a lysosomal enzyme which has different functions on the basis of protein and applied peptide cleavage. PURPOSE This research aimed to evaluate and compare the expression level o...

Pyogenic granuloma or granuloma pyogenicum is a well-known oral lesion. The name pyogenic granuloma is a misnomer since the condition is not associated with pus and does not represent a granuloma histologically. Pyogenic granuloma of the oral cavity is known to involve the gingiva commonly. Extragingivally, it can occur on the lips, tongue, buccal mucosa, palate, and the like. A history of trau...

Granulomas are classified as immune or foreign body granulomas. Of these, the immune granulomas, a hallmark of granulomatous inflammation, are closely related to cell-mediated immune responses. The aim of the present study is to characterize immune granuloma cells in 33 patients with granulomatous inflammation focusing on the expression of CD205 (DEC205), a cell surface marker of antigen presen...

AEGCG: annular elastolytic giant cell granuloma INTRODUCTION Annular elastolytic giant cell granuloma (AEGCG) is an uncommon condition belonging to the family of elastolytic granuloma, which also includes actinic granuloma, atypical necrobiosis lipoidica of the face and scalp, and Miescher’s granuloma. Classification of AEGCG as a distinct entity has been controversial. Although some consider i...

The method of Garra and Baygorria, for localized antibody production, has been adapted for obtaining high-titered and monospecific antibodies against the murine toxin of Yersinia pestis. A hollow, perforated plastic golf ball surgically implanted under the skin of rabbits induced the formation of a granuloma. When the murine toxin of Y. pestis was injected directly into the granulomatous cavity...

Granuloma annulare is a benign, inflammatory dermatosis of uncertain etiology, classically presenting with localized or generalized, skincoloured to violaceous, non-scaly, dermal papules/nodules which may be discrete coalesce form annular roundish plaques. While granuloma benign disease, little known about its pathophysiology, and comorbidities. Furthermore, treatment remains poorly standardize...

Background Craniofacial clefts are congenital anomalies which pose a management challenge to cleft surgeons, especially in developing countries. The aim of this study is to share our experience regarding the management of these atypical facial clefts. Patients and Methods This prospective study was carried out from May 2009 to May 2014 at Federal Medical Centre, Nguru, Nigeria. Diagnosis was ...

median cleft is the midline cleft of the lip. it develops due to incomplete or failed fusion of the median nasal prominence. it can present with minimal deformities such as involvement of the vermilion border, or complex clefting of the midline structures and brain. median clefts are broadly classified as true and false clefts. this case report describes a rare case of median cleft of the upper...