The incidence of cleft lip in CL/Fr mouse is 18-2500. The purpose of this study is to clarify the cause of cleft lip in CL/Fr mouse using whole embryo culture system which is a useful technique in studying the development of mammalian embryos in vitro. We examined the incidence of cleft lip in CL/Fr and F, mouse embryo (male CL/Fr x female C57BL/6) in vitro. The embryos were explanted on day 10...

introduction: a cleft lip with or without a cleft palate is one of the major congenital anomalies observed in newborns. this study explored the risk factors for oral clefts in gorgan, northern iran.  materials and methods: this hospital-based case-control study was performed in three hospitals in gorgan, northern iran between april 2006 and december 2009. the case group contained 33 newborns wi...

BACKGROUND Orofacial clefts are a group of frequently observed congenital malformations often requiring multiple hospital admissions over the lifespan of affected individuals. The aim of this study was to describe the total-population hospital admissions with principal diagnosis of cleft lip and/or palate in Australia over a 10 year period. METHODS Data for admissions to hospitals were obtain...

PURPOSE To evaluate long-term results in the bilateral cleft lip repair by Mulliken's method, using anthropometric measurements, we assessed the growth of the nose and upper lip after the operation by comparing with those from 30 children without bilateral cleft lip. MATERIALS AND METHODS Forty-four patients had their bilateral cleft lip and nasal deformity repaired simultaneously by Mulliken...

Introduction: Orofacial clefts are among the most common congenital anomalies. Patients presenting with orofacial clefts often require surgery or other complex procedures. A cleft lip or palate can be a single anomaly or a part of multiple congenital anomalies. The reported prevalence of cleft disease and associated anomalies varies widely across the literature, and is dependent on the diagnost...

Tooth disorders in the anterior region of the maxilla are very common among patients with cleft lip, alveolar bone and palate. The authors concentrate on dental disorders, erupting problems and root development, specifying dental anomalies - especially regarding the lateral incisor, central incisor and canine. Disorders may relate to the shape of the tooth, its location, size, number and they c...

OBJECTIVE The purpose of this present study was to compare, by means of 3D digital casts, the anterior transverse dimension of the dental arch of newborns with and without cleft lip and palate. MATERIAL AND METHODS The sample was composed of ninety-four children aged from 3 to 9 months divided into three study groups: Group I - children without craniofacial deformities (control group); Group ...

OBJECTIVE To propose a community-based network system and interdisciplinary management for children with cleft lip/ palate, applicable to Thailand and other developing countries. MATERIAL AND METHOD A network was developed for the care of patients with cleft lip/palate by combining primary health care, community-based rehabilitation and institutional expertise (Tawanchai Center), Five worksho...

nasoalveolar molding represents a paradigm shift from traditional presurgical orthopedics in the care of cleft lip and palate patients which has been applied increasingly in the past two decades. this article is a review of recent literature apropos of objectives, appliances, complications and short and long term effects of this technique.